Publications by authors named "Upender Sharma"

Fine-needle aspiration cytology (FNAC) has emerged as simple, minimally invasive, low-cost, outpatient diagnostic modality for the evaluation of nodules caused by parasites. Cysticercosis is caused by larval stage of , pork tapeworm. It is endemic in Southeast Asia, Latin America and South Africa.

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Background: The role fine-needle aspiration (FNA) in the diagnosis of salivary gland lesions has evolved over the years. Although clinical and radiological parameters help to narrow the differential diagnosis the tissue diagnosis still remains the gold standard.

Materials And Methods: This study is from January 2013 to December 2015 in our Department of Pathology where 170 salivary gland lesions were aspirated.

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Epstein-Barr virus (EBV) is the first herpes virus to be completely sequenced. It is implicated in diseases from the benign infectious mononucleosis to malignant nasopharyngeal carcinoma, Burkitt's lymphoma and primary CNS lymphoma in AIDS patients. It has also been found to be associated with some miscellaneous diseases like chronic fatigue syndrome, multiple sclerosis etc.

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Article Synopsis
  • Primary Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) of the kidney is a rare type of cancer that can be confused with other tumors, and this case involves a 35-year-old woman diagnosed using advanced techniques.
  • The diagnosis was made through fine needle aspiration cytology (FNAC), which revealed malignant round cells, and was confirmed with immunohistochemistry (IHC) and reverse-transcriptase polymerase chain reaction (RT-PCR).
  • This case highlights the importance of using molecular techniques for accurate diagnosis, emphasizes the findings of strong positivity for specific markers (CD99 and vimentin), and notes the presence of metastases to a cervical lymph node.
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Diagnosis of a high-grade sarcoma on fine needle aspiration cytology (FNAC) may not pose any difficulty; however, further sub-typing is sometimes difficult. The clinical data, investigations, and finer points on cytomorphology may help for proper categorization of the tumor, however, we encountered a case of orbital sarcoma in an Human Immunodeficiency Virus (HIV) positive patient, in which further sub-typing was difficult even on histopathology and immunohistochemistry was helpful. The diagnostic difficulties on FNA cytology smears as well as histopathology are highlighted.

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Sentinel lymph nodes (SLN) isolated in 40 patients of breast carcinoma (stage T(1)/T(2)) were evaluated intraoperatively by imprint cytology and frozen section. Rapid immunohistochemistry (IHC) was done in cases where both imprint smears and frozen sections were negative for any metastatic tumor deposits. The results of these different techniques were compared with postoperative paraffin sections taken as "Gold Standard.

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