Publications by authors named "Upasana Bharadwaj"

Objectives: To investigate the association between magnetic resonance imaging (MRI)-based ligamentum teres lesions (LTL) and structural hip degeneration.

Methods: Bilateral 3-T hip MRIs of participants (n = 93 [36 men]; mean age ( ± SD) 51 years ± 15.4) recruited from the community and the orthopedic clinic of a single medical center were included.

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Background: Meniscal root tears can lead to early knee osteoarthritis and pain. This study aimed (1) to compare clinical and radiological outcomes between patients who underwent arthroscopic meniscal root repair after meniscal root tears and those who received non-surgical treatment, and (2) to identify whether baseline MRI findings could be potential predictors for future treatment strategies.

Methods: Patients with meniscal root tears were identified from our picture archiving and communication system from 2016 to 2020.

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Article Synopsis
  • AI has huge potential in medical imaging, especially for diagnosing spinal issues, improving efficiency and accuracy of interpretations.
  • The review examines different AI algorithms and techniques used in spine imaging, focusing on their diagnostic benefits and challenges.
  • It also discusses future directions for effectively incorporating AI into the workflow of spine imaging.
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Objective: To investigate the associations of thigh muscle and fat volumes with structural abnormalities on MRI related to knee osteoarthritis.

Materials And Methods: MRI studies of the thighs and knees from 100 individuals were randomly selected from the Osteoarthritis Initiative Cohort. Whole Organ MR Scoring (WORMS) and effusion-synovitis scoring were performed in all knee MRI.

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Objective: To assess the prevalence and clinical implications of variant sciatic nerve anatomy in relation to the piriformis muscle on magnetic resonance neurography (MRN), in patients with lumbosacral neuropathic symptoms.

Materials And Methods: In this retrospective single-center study, 254 sciatic nerves, from 127 patients with clinical and imaging findings compatible with extra-spinal sciatica on MRN between 2003 and 2013, were evaluated for the presence and type of variant sciatic nerves, split sciatic nerve, abnormal T2-signal hyperintensity, asymmetric piriformis size and increased nerve caliber, and summarized using descriptive statistics. Two-tailed chi-square tests were performed to compare the anatomical variant type and clinical symptoms between imaging and clinical characteristics.

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Article Synopsis
  • - This study aimed to evaluate a deep learning model for diagnosing central canal stenosis, neural foraminal stenosis, and facet arthropathy from lumbar spine MRI images.
  • - Researchers used 200 MRI scans from 2008 to 2019, with the data split into training, validation, and testing sets, and developed models for segmentation and classification, achieving high accuracy metrics.
  • - The results indicated that deep learning models can effectively and understandably automate the evaluation of lumbar spine conditions, showing good performance in multi-class and binary classifications.
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Magnetic Resonance Imaging (MRI) offers strong soft tissue contrast but suffers from long acquisition times and requires tedious annotation from radiologists. Traditionally, these challenges have been addressed separately with reconstruction and image analysis algorithms. To see if performance could be improved by treating both as end-to-end, we hosted the K2S challenge, in which challenge participants segmented knee bones and cartilage from 8× undersampled k-space.

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Article Synopsis
  • Calcifying fibrous tumor is a rare kind of tumor that seems harmless and has a special look under a microscope.
  • A 25-year-old man discovered a painful mass on his right foot that had been growing for 4 years.
  • Doctors used X-rays and MRI scans to diagnose it, finding it was a calcifying fibrous tumor, which, although uncommon, can appear in soft tissues like the foot.
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Study Design: In vivo retrospective study of fully automatic quantitative imaging feature extraction from clinically acquired lumbar spine magnetic resonance imaging (MRI).

Objective: To demonstrate the feasibility of substituting automatic for human-demarcated segmentation of major anatomic structures in clinical lumbar spine MRI to generate quantitative image-based features and biomechanical models.

Setting: Previous studies have demonstrated the viability of automatic segmentation applied to medical images; however, the feasibility of these networks to segment clinically acquired images has not yet been demonstrated, as they largely rely on specialized sequences or strict quality of imaging data to achieve good performance.

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Background: Modic changes (MCs) are the most prevalent classification system for describing magnetic resonance imaging (MRI) signal intensity changes in the vertebrae. However, there is a growing need for novel quantitative and standardized methods of characterizing these anomalies, particularly for lesions of transitional or mixed nature, due to the lack of conclusive evidence of their associations with low back pain. This retrospective imaging study aims to develop an interpretable deep learning-based detection tool for voxel-wise mapping of MCs.

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Objective: To qualitatively evaluate the utility of zero echo-time (ZTE) MRI sequences in identifying osseous findings and to compare ZTE with optimized spoiled gradient echo (SPGR) sequences in detecting knee osseous abnormalities.

Materials And Methods: ZTE and standard knee MRI sequences were acquired at 3T in 100 consecutive patients. Three radiologists rated confidence in evaluating osseous abnormalities and image quality on a 5-grade Likert scale in ZTE compared to standard sequences.

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The spine is an articulated, 3D structure with 6 degrees of translational and rotational freedom. Clinical studies have shown spinal deformities are associated with pain and functional disability in both adult and pediatric populations. Clinical decision making relies on accurate characterization of the spinal deformity and monitoring of its progression over time.

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Purpose: To test the hypothesis that artificial intelligence (AI) techniques can aid in identifying and assessing lesion severity in the cartilage, bone marrow, meniscus, and anterior cruciate ligament (ACL) in the knee, improving overall MRI interreader agreement.

Materials And Methods: This retrospective study was conducted on 1435 knee MRI studies ( = 294 patients; mean age, 43 years ± 15 [standard deviation]; 153 women) collected within three previous studies (from 2011 to 2014). All MRI studies were acquired using high-spatial-resolution three-dimensional fast-spin-echo CUBE sequence.

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