Publications by authors named "Ungan I"

Background: Atrial fibrillation (AF) prevalence in patients with acute myocardial infarction (MI) ranges from 3% to 25%. However demographic, clinical, and angiographic characteristics of AF patients who admitted with de novo MI are unclear. The aim of this study was to investigate the prevalence of patients presenting with de novo MI with AF.

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This recent Turkish Myocardial Infarction registry reported that guidelines are largely implemented in patients with acute myocardial infarction (MI) in Turkey. We aimed to obtain up-to-date information for short- and midterm outcomes of acute MI. Fifty centers were selected using probability sampling, and all consecutive patients with acute MI admitted to these centers (between November 1 and 16, 2018) were enrolled.

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Article Synopsis
  • Myocardial infarction with non-obstructive coronary arteries (MINOCA) is recently defined and can occur despite normal coronary conditions, but its prevalence was previously unstudied in Turkey.
  • The MINOCA-TR study involved 1,626 patients from 32 hospitals who met criteria for MI and underwent coronary angiography, revealing a 6.7% prevalence of MINOCA among those screened.
  • MINOCA patients tended to be younger, had a higher proportion of females, and presented with fewer common risk factors compared to non-MINOCA patients, indicating distinct demographic and clinical characteristics.
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The aim of this study was to evaluate serum interleukin (IL)-17A levels in patients with coronary artery ectasia (CAE), the relationship between IL and 17A and CAE, and to determine the relationship between the severity of coronary ectasia and the level of IL-17A. In total, 41 patients (19 female and 22 male) with ischemic symptoms whose non-invasive cardiac tests were positive for myocardial ischemia, and in whom coronary artery ectasia were detected after coronary angiography, and 45 patients (32 female and 13 male) with normal coronary arteries were included in this study. Echocardiographic assessments were performed.

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Introduction: Inflammation plays a key role in atherosclerosis, and discovering new biomarkers of inflammation is becoming important in order to uncover the pathogenesis of atherosclerotic coronary artery disease (CAD). Recent studies have focused on polymorphonuclear neutrophils. It has been suggested that human neutrophil peptide 1-3 (HNP1-3) is proatherogenic.

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Article Synopsis
  • The study investigates the relationship between vitamin D and parathormone levels with isolated coronary artery ectasia (CAE) among 93 participants, including 47 CAE patients and 46 controls.
  • Serum vitamin D levels were significantly lower in the CAE group, while parathormone levels were significantly higher compared to controls.
  • Despite these differences, no correlation was found between vitamin D levels and the severity of CAE as measured by the Markis classification.
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Objective: We aimed to investigate whether soluble CD40 ligand (CD40L) levels are higher in patients with isolated coronary artery ectasia (CAE) compared to patients with angiographically normal coronary arteries and those with stable coronary artery disease (CAD).

Materials And Methods: In all, 55 patients with isolated CAE without stenosis, 55 with stable CAD, and 55 control participants with angiographically normal coronary arteries were included. The CAE severity was determined according to the Markis classification.

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Background: Preeclampsia (PE) is a multisystemic disorder characterized by hypertension and proteinuria that is specific to pregnancy and associated with maternal and fetal morbidity-mortality.

Aim: To assess right heart structure and function in PE by echocardiography using conventional and tissue Doppler techniques.

Methods: In total, 67 women with untreated PE and 46 matched healthy pregnant women were included.

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Objective: Cardiac X syndrome is defined in patients with normal coronary angiogram who has typical chest pain and objective myocardial ischemia evidence. Recent studies have evaluated the association between vitamin D deficiency (vit D def) and cardiovascular diseases. Our aim of this study was to compare serum vit D levels in patients with syndrome X and controls.

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Coronary artery ectasia (CAE) is associated with coronary artery disease (CAD). The underlying pathophysiology of CAE is not fully understood. α-antitrypsin (A1AT) plays a role in the tissue protease system, and AAT-1 deficiency (A1ATD) has been shown to be related to CAD.

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Purpose: The aim of this study is to evaluate the correlation between epicardial adipose tissue thickness and oxidative stress parameters in patients with polycystic ovarian syndrome.

Methods: The study included 35 patients with PCOS and 35 healthy women. Transthoracic echocardiography was used to measure the epicardial adipose tissue thickness (EATT) of all patients.

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The risk for cardiovascular diseases and type 2 diabetes mellitus significantly increases in the patient population with metabolic syndrome (MeS). The present study aimed to investigate the association between the epicardial adipose tissue thickness (EATT) and the oxidative stress parameters in MeS patients. The study included 181 patients as a patient group of 92 consecutive patients with MeS and a control group of 89 consecutive patients with similar age and gender.

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Article Synopsis
  • This study explores the psychological profiles of patients with non-cardiac angina (NCA) compared to those with acute coronary syndrome (ACS), focusing on temperament, anxiety, and depression.
  • The research involved 63 patients (41 with NCA and 22 with ACS), using specific scales to assess their psychological characteristics and sociodemographic data.
  • Results showed no significant differences in most psychological measures between the two groups, except for a notably higher irritability in the NCA group, suggesting the need for further investigation into the psychological aspects of NCA.
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Patients with angiographically normal coronary arteries sometimes exhibit delayed clearance of contrast medium. This contrast layering (CL) was tested with intravascular ultrasound (IVUS) and markers of endothelial dysfunction and oxidative stress. The study group (n = 26) consisted of patients with CL and the control group (n = 32) comprised patients with normal coronary arteries despite angina symptoms.

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Introduction: Platelets play a major role in thromboembolic events. Increased mean platelet volume (MPV) indicates higher platelet reactivity and also a tendency to thrombosis. Patent foramen ovale (PFO), persistence of the fetal anatomic shunt between right and left atria, is strongly associated with cryptogenic stroke.

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Objective: This study aimed to evaluate the serum gamma-glutamyltransferase (GGT) levels as an indirect marker of elevated oxidative stress in patients with dilated ascending aorta.

Methods: The study was designed as an observational cross-sectional controlled study. One hundred consecutive patients with dilated ascending aorta and 50 consecutive controls with normal ascending aorta diameter were selected for the study by comprehensive transthoracic echocardiography (TTE).

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Objectives: The aim of this single-center prospective study is to investigate the silent and clinically apparent cerebral embolic events after transcatheter closure of atrial septal defect (ASD) and patent foramen ovale (PFO).

Background: Although transcatheter closure of ASD and PFO is a widely accepted technique and has been proven to be safe and effective with different kinds of devices, there are few studies in the literature that report the peri-interventional cerebral embolism risk and neurological complications. In this study, we investigated the peri-interventional cerebral embolism incidence with diffusion-weighted magnetic resonance imaging (DW-MRI) and its relation to patients' clinical neurologic examination findings and plasma neuron-specific enolase (NSE) levels.

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Hypertrophic cardiomyopathy is a well-known clinical entity. Hypertrophy engraving the left ventricular apex, so called, apical hypertrophic cardiomyopathy (characterized by the giant negative T waves at ECG and a "spade-like" view of left ventricle) is very rare variant of the pathology. In this report, we present a 51-year-old patient with apical hypertrophic cardiomyopathy together with a brief review of the literature.

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