Publications by authors named "Umut Sarpel"

Article Synopsis
  • Gastrointestinal stromal tumors (GISTs) are a type of sarcoma found in the muscular layer of the gastrointestinal tract, primarily occurring in the stomach and small intestine.
  • The main treatment is surgical resection, with various techniques available, though extensive surgical measures like lymphadenectomy are usually not needed.
  • Tyrosine kinase inhibitors can be used before surgery to shrink tumors and after surgery for high-risk cases, and in some instances, removing metastases can enhance patient outcomes.
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Gallbladder Cancer.

Surg Clin North Am

December 2024

Article Synopsis
  • * Risk factors for gallbladder cancer include gender, age, history of gallbladder disease, and the size of polyps, and its global occurrence varies significantly.
  • * Effective management includes imaging, possible staging laparoscopy, and radical surgery, with ongoing clinical trials exploring neoadjuvant therapy, while early detection remains critical for better survival chances.
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Article Synopsis
  • The PRECINCT study is a multicenter analysis of surgical documentation and disease incidence in patients with peritoneal tumors, focusing on the surgical peritoneal cancer index (sPCI) and its variations across centers.
  • Among 707 enrolled patients from September 2020 to December 2021, the study found that different morphological terminologies were used to describe peritoneal lesions, with the most common being "normal peritoneum," "tumor nodules," and "confluent disease."
  • The research revealed that the incidence of pathologically confirmed disease was higher in cases with more severe lesion scores and suggested that using frozen section analysis could be beneficial, indicating the need for larger studies correlating imaging and pathology.
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Article Synopsis
  • - Access to minimally invasive surgery (MIS) in Sub-Saharan Africa is limited, but the Kyabirwa Surgical Center (KSC) was established in Uganda through collaboration between Mount Sinai and local staff, featuring training programs that blend in-person and telementoring.
  • - The KSC is equipped with reliable solar power and high-speed internet, allowing a Ugandan surgeon, JOD, to benefit from extensive MIS training and perform surgeries with remote guidance from New York surgeons.
  • - Between October 2021 and February 2024, JOD successfully performed 61 laparoscopic surgeries with minimal postoperative complications, demonstrating that telementoring can effectively enhance surgical care in underserved regions.
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Background: Black patients have higher hepatocellular carcinoma (HCC)-related mortality than White patients and more often develop HCC in non-cirrhotic liver. HCC surveillance is primarily directed toward cirrhotic patients. We aimed to characterize HCC in non-cirrhotic patients and to identify factors associated with HCC beyond Milan criteria.

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Importance: Despite improvements in perioperative mortality, the incidence of postoperative surgical site infection (SSI) remains high after pancreatoduodenectomy. The effect of broad-spectrum antimicrobial surgical prophylaxis in reducing SSI is poorly understood.

Objective: To define the effect of broad-spectrum perioperative antimicrobial prophylaxis on postoperative SSI incidence compared with standard care antibiotics.

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