Publications by authors named "Umut Cakir"

Article Synopsis
  • Hypoxia is increasingly recognized as a key factor that helps brain cells adapt to low oxygen levels and reduced metabolism, leading to what the authors call "functional hypoxia."
  • The study investigates the effects of combined mild inspiratory and functional hypoxia during motor-cognitive training in a group of 20 participants, including healthy individuals and those with depression or autism spectrum disorder.
  • Initial findings suggest that this training under low oxygen conditions is well-tolerated and may improve well-being, cognitive performance, physical fitness, and affect immune cell responses, warranting further research with a controlled trial to better assess the benefits.
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How many different proteins can be produced from a single spliced transcript? Genome annotation projects overlook the coding potential of reading frames other than that of the reference open reading frames (refORFs). Recently, alternative open reading frames (altORFs) and their translational products, alternative proteins, have been shown to carry out important functions in various organisms. AltORFs overlapping refORFs or other altORFs in a different reading frame may be involved in one fundamental mechanism so far overlooked.

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Article Synopsis
  • - The study aimed to examine the effects of bonsai (a type of synthetic drug) use alone and in combination with other substances in 49 patients who showed positive urinary metabolite tests after going to the emergency department between December 2014 and January 2016.
  • - Results indicated that a significant number (69.4%) of patients used additional drugs along with bonsai, with the most common being tetrahydrocannabinol and alcohol, and the typical symptoms observed included tachycardia (75.5%).
  • - The group using bonsai and other drugs had a higher Glasgow Coma Score upon admission and longer symptom remission and hospitalization times compared to those who only used bonsai, indicating more severe health impacts
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Background And Aims: Acute pain is the most common reason for visits to the emergency department (ED). The underuse of analgesics occurs in a large proportion of ED patients. The physician's accurate assessment of patients' pain is a key element to improved pain management.

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Objective: Early and accurate diagnosis of acute appendicitis (AA) with ultrasound (US) can minimize the morbidity and mortality of the patients. In this regard, US can help emergency physicians (EPs) in the diagnosing process and clinical decision making for AA. Therefore, we primarily aimed to evaluate the effectiveness of point-of-care US (POCUS) in clinical decision making of EPs for the diagnostic evaluation for AA in the emergency department (ED).

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