Publications by authors named "Umut Cagiral"
Article Synopsis
- Testing the biocompatibility of dental materials is crucial and this study focused on four specific materials: Mineral Trioxide Aggregate, Biodentine, Harvard BioCal-CAP, and Oxford ActiveCal PC.
- The evaluation used zebrafish embryos and larvae to assess survivability, hatching rates, and apoptosis through various toxicity tests.
- Results indicated that higher concentrations of these materials negatively affected survival and hatching, with Biodentine and Oxford ActiveCal PC showing better biocompatibility than Mineral Trioxide Aggregate.
Tumor necrosis factor-α (TNF-α) is a ligand that induces both intrinsic and extrinsic apoptotic pathways in HeLa cells by modulating complex gene regulatory mechanisms. However, the full spectrum of TNF-α-modulated epitranscriptomic mA marks is unknown. We employed a genomewide approach to examine the extent of mA RNA modifications under TNF-α-modulated apoptotic conditions in HeLa cells.
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