Pierre Fauchard (1678-1761): Pioneering Dental Surgeon of the Enlightenment Age.

Pierre Fauchard, widely referred to as the "Father of Modern Dentistry," fundamentally transformed the field with his seminal 1728 publication,  Born circa 1677 in Brittany, France, Fauchard's early exposure to severe dental conditions during his naval service catalyzed his pursuit of advancements in dental science. Upon transitioning from naval service to establish a practice in Angers, and subsequently gaining acclaim in Paris, Fauchard systematically documented and organized dental practices, encompassing oral surgery, orthodontics, periodontics, and prosthodontics, thereby laying the foundational framework for contemporary dental practices. Fauchard's innovations included the use of materials such as lead, tin, and gold for dental fillings and the introduction of early orthodontic techniques, notably the  His treatise also emphasized the importance of preventive care and oral hygiene, which provided a basis for modern dental hygiene protocols.

Effects of N-acetyl-L-cysteine against apical periodontitis in rats with adriamycin-induced cardiomyopathy and nephropathy.

Aim: This study aimed to investigate the potential protective effects of N-acetyl-L-cysteine (NAC) against apical periodontitis (AP) in rats with adriamycin (ADR)-induced kidney and heart diseases.

Methodology: Fourty-eight Wistar albino rats were divided into six groups: (1) Control group, (2) ADR group (1 mg/kg/day ip for 10 days), (3) AP Group (1st mandibular molar tooth), (4) AP + ADR Group, (5) AP + NAC group (150 mg/kg/day ip), and (6) AP + ADR + NAC group. After 3 weeks, the rats were decapitated and blood and tissue samples (heart, kidney, and jaw) were collected.

Effect of bromelain on periodontal destruction and alveolar bone in rats with experimental periodontitis.

Purpose: Several substances that have anti-inflammatory, antiproteinase, and anti-infective properties have been evaluated as modulators of the inflammatory response in periodontal disease. However, evidence for the anti-inflammatory and antioxidative activities of bromelain is limited. This study evaluated the impact of systemically administered bromelain on the progression of experimental periodontitis.

Influence of voxel size and filter type on detecting vertical root fracture using cone-beam computed tomography.

Vertical root fractures (VRFs) can start at any level of the root and progress longitudinally to the coronal attachment. This study aimed to investigate the effects of different exposure parameters used when obtaining CBCT scans in detecting simulated VRFs. Hence, 80 intact human mandibular single-rooted pre-molar teeth without root fractures were included in the study.

Decreased Functioning and Contents of Worries Associated with Anxiety or Depression Symptom Levels Within Patients Hospitalized with COVID-19 Infection.

Background: High levels of anxiety and depression symptoms have been reported in patients with COVID-19 compared to the general population. These symptoms were related to variables such as gender, age, and education level with anxiety/depression levels. We aimed to determine the relationship between anxiety and depression symptoms and epidemic-related decreased functioning, worry, and quality of life (QoL).

Linguistic Equivalence, Validity and Reliability Study of the Mind Excessively Wandering Scale.

Introduction: The main objective was to study the linguistic equivalence, validity and reliability of the transliterated Turkish version of Mind Excessively Wandering Scale (MEWS) developed by Prof. Philip Asherson in England (2016). Mind excessively wandering defines uncontrolled mental phenomena, which is proposed as the psychological counterpart of Default Mode Network in literature.

Evaluation of the oxytocin effect in a rat model with experimental periodontitis.

The aim of the present study was to evaluate the inhibitory effects of oxytocin on the development of periodontitis based on its properties against bone loss and resorption. Thirty-two Wistar albino rats were divided into four equal groups: control, periodontitis + saline, periodontitis + 0.5 mg/kg/day oxytocin, and periodontitis + 1 mg/kg/day oxytocin.

Relationship of NLRP3 inflammasome with periodontal, endodontic and related systemic diseases.

NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) is an inflammasome associated with oral and general health. There is a bidirectional relationship between the oral cavity and systemic health. The primary reason for this situation is the similarity in pathways for chronic inflammatory diseases both in the oral cavity and systemically.

The Impact of Laser-Activated and Conventional Irrigation Techniques on Sealer Penetration into Dentinal Tubules.

The present study was aimed at comparing the efficacy of 1-hydroxyethylidene-1, 1-diphosphonic acid (HEDP) and ethylenediaminetetraacetic acid (EDTA) by using various final irrigation techniques on penetration of sealer. Traditional irrigation of root canals with a syringe limits the ability of sealer penetration. Various irrigants and activation techniques, including sonic and ultrasonic devices and various kinds of lasers, have been introduced to improve penetration of sealers into dentinal tubules.

Postpartum evaluation of the role of maternal characteristics and mode of delivery on maternal attachment, anxiety and depression; a study conducted in Turkey'.

Background And Aim: The primary aim of this study was to compare mother-infant bonding (MIB) in patients who delivered vaginally and who delivered with C/S using Maternal Attachment Inventory (MAI), Edinburgh Postnatal Depression Scale (EPDS) and Postpartum Specific Anxiety Scale (PSAS) in the Turkish population. Secondary aim was to evaluate the correlations between the MAI, EPDS and PSAS scores and their association with sociodemographic data.

Methods: A total of 200 patients were divided into two groups.

Does α-lipoic acid therapeutically effective against experimentally induced-acute pulpitis in rats?

The purpose of the study was to investigate the therapeutic effects of α-lipoic acid (ALA) on an induced-acute pulpitis model in rats. Twenty-four Wistar albino rats were randomly divided into three groups: control, induced-acute pulpitis (PULP) and PULP + ALA groups. In the PULP and PULP + ALA groups, the crowns of the maxillary left incisors were removed horizontally.

Efficacy of Laser-Activated Irrigation and Conventional Techniques in Calcium Hydroxide Removal from Simulated Internal Resorption Cavities: Micro-CT Study.

This study aimed to evaluate the effectiveness of different irrigant-activation techniques for eliminating calcium hydroxide from an internal root canal resorption cavity by using microcomputed tomography (micro-CT). Several techniques and irrigants are inadequate for the complete removal of calcium hydroxide from an internal root resorption cavity. Recently, a few studies have investigated the effectiveness of various methods, but there has been no micro-CT study that compares the effectiveness of photon-induced photoacoustic streaming (PIPS) and shock wave enhanced emission photoacoustic streaming (SWEEPS) techniques.

An overview of the 35 years of research in the oral radiology: a bibliometric analysis.

Objectives: The aim of this study was to provide a bibliometric overview of the oral radiology journal output, contents, and leading trends, and also include a detailed authorship analysis by evaluating the top contributors, and their geographic distributions between 1985 and 2020 years.

Methods: The databases available on the Scopus and journal's Web Page were searched to identify the all published articles and reports with no restriction regarding publication year or study design. Seven hundred and seventy-seven articles were included and analyzed for the following bibliometric criteria: publication title, authorship, publication year, coauthors, institution of origin, country of origin, collaborating institution and countries, article category, study field, and number of citations based on the Scopus and Google Scholar.

Role of NLRP3 inflammasome in COVID-19 and periodontitis: Possible protective effect of melatonin.

Daily new information emerges regarding the COVID-19, infection of SARS-CoV-2, which is considered a global pandemic. Angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) are required to complete the viral invasion pathway and are present in the oral mucosa, gingiva and periodontal pocket. Thus, increasing the likelihood of periodontitis and gingivitis caused by COVID-19.

The circadian clock gene : Role in COVID-19 and periodontitis.

The physiological processes of most living organisms follow a rhythmic pattern, which is controlled by the interaction between environmental cues and the internal circadian timing system. Different regulatory circadian genes are expressed in most cells and tissues, and disruptions in the sleep-wake cycle affect these genes, which may result in metabolic disorders and cause alterations of the immune system. The manifestations of these disrupted genes are evident in inflammatory conditions such as periodontitis and some viral diseases, including COVID-19.

Anti-Inflammatory Effects of Melatonin and 5-Methoxytryptophol on Lipopolysaccharide-Induced Acute Pulpitis in Rats.

Aim: The aim of this study was to investigate the possible therapeutic impacts of two pineal hormones, melatonin and 5-methoxytryptophol (5-MTX), in a rat model of acute pulpitis by analyzing biochemical and histopathological parameters.

Methods: This research was done using 32 male and female Wistar albino rats with weight between 200 and 250 g. The rats were randomly divided into four groups: a control group (rats without any treatment), acute pulpitis (AP) group, AP+melatonin group, and AP+5-MTX group.

Diagnosing odontogenic sinusitis: An international multidisciplinary consensus statement.

Background: Odontogenic sinusitis (ODS) is distinct from non-odontogenic rhinosinusitis, and often requires multidisciplinary collaboration between otolaryngologists and dental providers to make the diagnosis. The purpose of this study was to develop international multidisciplinary consensus on diagnosing ODS.

Methods: A modified Delphi method was used to assess for expert consensus on diagnosing bacterial ODS.

The top risk factors for endodontic flare-up: a Monte Carlo simulation.

Objectives: The aim of this study was to analyze the strength of risk factors related to endodontic flare-ups and rank them in order of their importance MATERIALS AND METHODS: A systematic literature search of PubMed, Cochrane Central Register of Controlled Trials, Scopus, and ISI Web of Knowledge, and grey literature was conducted up to November 2019. One hundred ninety-eight publications were identified. Twelve records fulfilled the eligibility criteria, and eight significant risk factors for flare-up, namely, "Periapical lesion," "multiple-visit treatment," "preoperative pain," "necrotic teeth," "female gender," "retreatment," "percussion pain," and "analgesics," were selected to construct the simulation model.

Temperament, Character, and Defense Mechanism Changes With Treatment in Depression: A 9-Month Naturalistic Follow-up.

The aim of this study was to evaluate the changes in temperament, character, and defense mechanisms with the treatment and remission in patients with major depressive disorder. The study was designed as a longitudinal observational follow-up study of patients with repeated measures at 0, 12, and 36 weeks. In baseline comparisons, the major depression group showed higher harm avoidance and novelty seeking scores and lower self-directness and mature defense styles scores compared with healthy controls.

Protective effect of alpha-lipoic acid against apical periodontitis-induced cardiac injury in rats.

This study was designed to assess the possible protective effect of alpha-lipoic acid (ALA) on apical periodontitis (AP)-induced cardiac injury. Wistar albino rats were randomized into four groups: control; ALA; AP; and ALA + AP. Rats of the control and ALA groups were not endodontically treated, but saline and ALA (100 mg kg ) were administered.

Is it possible to determine the level of functional impairment that distinguishes the patients with ADHD from those without ADHD?

Introduction: Functional impairment in attention deficit hyperactivity disorder (ADHD) can occur in many areas such as in family, social activities, and problems related to school and may also persist during adulthood. The Weiss Functional Impairment Rating Scale-Parent Form (WFIRS-P) is designed to measure the functional impairment related to ADHD symptoms. The aim of this study was to determine the level of functional impairment that distinguishes the patients with ADHD who were diagnosed through semi-structured interviews from those without ADHD.

Risk Factor in Endodontic Treatment: Topographic Evaluation of Mandibular Posterior Teeth and Lingual Cortical Plate Using Cone Beam Computed Tomography (CT).

BACKGROUND Topographic relationships of mandibular posterior teeth with mandibular cortical plate are extremely important both in terms of infection spread and endodontic and surgical procedures to be performed. The aim of this study was to determine the relationship between root apex of the mandibular posterior teeth and lingual plate of the mandible. MATERIAL AND METHODS CBCT data of 138 patients were retrospectively analyzed.

Evaluation of the Relationship Between Attention Deficit Hyperactivity Disorder Symptoms and Chronotype.

Introduction: The aim of the study is to investigate the relationship between circadian characteristics and behavioral problems in children with Attention Deficit Hyperactivity Disorder (ADHD) (n=53), and to compare this group with healthy controls (n=38).

Method: Fifty-three medication-free children with ADHD, aged 6-12 years, and 38 healthy children, age and sex matched, participated. Parents completed the Conners' Parent Rating Scale-Revised, the Children's Chronotype Questionnaire (CCTQ), and the Children's Sleep Habits Questionnaire (CSHQ) to assess sleep variables.

Determination of the Minimum Inhibitory Concentrations of Alexidine and Chlorhexidine Against Enterococcus faecalis and Candida albicans: An In Vitro Study.

Introduction: The root canal system must be mechanically instrumented and chemically cleaned using various antimicrobial irrigants in a sequential manner or in combination for the elimination of necrotic pulp tissue and reducing the number of root canal bacteria. For this reason, new methods and materials are continuously being developed to achieve the objectives of endodontic treatment.

Materials And Methods: E.