Evaluation of Brain Electrical Activity of Visual Working Memory with Time-Frequency Analysis.

The term visual working memory (VWM) refers to the temporary storage of visual information. In electrophysiological recordings during the change detection task which relates to VWM, contralateral negative slow activity was detected. It was found to occur during the information is kept in memory and it was called contralateral delay activity.

The effect of DNA repair gene variants on COVID-19 disease: susceptibility, severity, and clinical course.

Oxidative stress (OS), which leads to DNA damage, plays a role in the pathogenesis of Coronavirus disease 2019 (COVID-19). We aimed to evaluate the role of DNA repair gene variants [X-ray repair cross complementing 4 () rs28360071, rs6869366, and X-ray cross-complementary gene 1 ( rs25487] in susceptibility to COVID-19 in a Turkish population. We also evaluated its effect on the clinical course of the disease.

The suppressor of cytokine signaling-1 () gene polymorphism and promoter methylation correlate with the course of COVID-19.

The suppressor of the cytokine signaling-1 (SOCS1) gene is a short sequence located on chromosome 16 that functions to induce an appropriate immune response and is an essential physiological regulator of interferon (IFN) signaling. In addition to comparing the global DNA and SOCS1 gene promoter methylation status between our patients with coronavirus disease 2019 (COVID-19) and healthy controls, this study demonstrates the effect of the SOCS1 rs33989964 polymorphism on patients with COVID-19. The study group included 139 patients diagnosed with COVID-19 in our hospital's clinics between June and December 2020, and the control group included 78 healthy individuals.

Mannose-Binding Lectin 2 Gene Polymorphism during Pandemic: COVID-19 Family.

Mannose-binding lectin 2 (MBL2) is a serine protease which is believed to be an important factor in the inherited immune system. In this article, we present a coronavirus disease 2019 (COVID-19) family of five patients: a 56-year-old father, a 51-year-old mother, two sons aged 23 and 21 years, and a 15-year-old daughter. According to the results of variant analysis performed, the father had homozygous mutant, the mother had homozygous normal, and the three children had heterozygous mutant genotype.

Initial complete blood count score and predicting disease progression in COVID-19 patients.

Introduction: Coronavirus has caused a pandemic since it was first detected in Wuhan in December 2019. The mortality rate is high in moderate and severe cases. Our study aimed to screen the CBC parameters as a useful predictive factor for COVID-19 resulting in critical illness.

Mannose binding lectin gene 2 (rs1800450) missense variant may contribute to development and severity of COVID-19 infection.

Background/objectives: COVID-19 followed a mortal course in some young patients without any underlying factors, however, it followed a very benign course in some very older individuals with multiple comorbidities. These observations question if some genetic factors may be related to the vulnerability and poor prognosis of the disease. In this study, we aimed to investigate whether MBL2 gene B variant at codon 54 (rs1800450) were related to the variabilities in clinical course of this infection.

Age related differences in the recognition of facial expression: Evidence from EEG event-related brain oscillations.

Facial Expression (FE) recognition is a major marker of emotional ability. Behavioral studies show that FE recognition ability decreases with aging. Studying how event-related brain oscillations change with normal aging is important to better understand the underlying mechanisms of emotional processes.

How visual stimulus effects the time perception? The evidence from time perception of emotional videos.

Time perception is defined as a subjective judgment on the elapsed time of an event. It can change according to both external and internal factors. There are two main paradigms of time perception; retrospective time perception (RTP) and prospective time perception (PTP).

Dancers and fastball sports athletes have different spatial visual attention styles.

Physical exercise and the training effects of repeated practice of skills over an extended period of time may have additive effects on brain networks and functions. Various motor skills and attentional styles can be developed by athletes engaged in different sports. In this study, the effects of fast ball sports and dance training on attention were investigated by event related potentials (ERP).

Does familial Mediterranean fever affect cognitive function in children? Electrophysiological preliminary study.

Objectives: Familial Mediterranean fever (FMF) is a periodic autoinflammatory disease with subclinical inflammation occurring between attacks. The aim of the study was to prospectively evaluate the cognitive function of children diagnosed with FMF that were under colchicine therapy and compare them with healthy controls through electrophysiologically event-related potentials (ERPs) study.

Methods: Twelve children with FMF and 12 healthy controls were included in the study.

Brain electrical activities of dancers and fast ball sports athletes are different.

Exercise training has been shown not only to influence physical fitness positively but also cognition in healthy and impaired populations. However, some particular exercise types, even though comparable based on physical efforts, have distinct cognitive and sensorimotor features. In this study, the effects of different types of exercise, such as fast ball sports and dance training, on brain electrical activity were investigated.

Event-related potentials during auditory oddball, and combined auditory oddball-visual paradigms.

The purpose of the current study was to investigate the properties of a new modification of the classical auditory oddball paradigm (auditory oddball paradigm combined with passive visual stimulation, AERPs + VEPs) and compare the scalp topography obtained with the new paradigm and the classical auditory oddball paradigm (AERPs) in healthy humans. The responses to bimodal stimulation, and to the classical oddball paradigm were similar to those reported in other studies in terms of location, amplitudes, and latencies of P1, N1, P2, N2, and P300. The new modification of the oddball paradigm produced P300 at fronto-central locations in contrast to centro-parietal locations during the classical oddball paradigm.

Event-related potentials to visual, auditory, and bimodal (combined auditory-visual) stimuli.

The purpose of this study was to investigate the response properties of event related potentials to unimodal and bimodal stimulations. The amplitudes of N1 and P2 were larger during bimodal evoked potentials (BEPs) than auditory evoked potentials (AEPs) in the anterior sites and the amplitudes of P1 were larger during BEPs than VEPs especially at the parieto-occipital locations. Responses to bimodal stimulation had longer latencies than responses to unimodal stimulation.

Necker cube reversals during long-term EEG recordings: sub-bands of alpha activity.

Reversible figures, such as the Necker cube, make up a well-known class of visual phenomena in which an invariant stimulus pattern gives rise to at least two different perceptual interpretations. A better understanding of the neurophysiological processes underlying perceptual reversals might help to disentangle bottom-up from top-down influences on multistable perception. Recently, we reported alpha activity decrease during multistable visual perception.

Auditory on- and off-responses and alpha oscillations in the human EEG.

In the present study, the wide band alpha and sub-bands of alpha in the auditory on- and off-responses to different stimulation frequencies were evaluated. Auditory on- and off-responses of 12 healthy volunteers (average 17 years old) were recorded from five locations (Fz, Cz, Pz, P3, and P4). The auditory stimuli of 80 dB SPL and 1000 ms duration were delivered at six different stimulation frequencies (f1-f6; 0.

N2 and P3 components of event-related potential in first-episode schizophrenic patients: scalp topography, medication, and latency effects.

Auditory N2 and P3 components of event-related potentials were assessed in first-episode schizophrenic and normal control subjects (n=12/group). P3 amplitude was decreased in the patients most prominently over the frontal areas in contrast to a widespread P3 amplitude decrease reported in chronic schizophrenia. Moreover, frontal attenuation of P3 amplitude was greater in the non-medicated compared with medicated patients, a finding that suggests frontal areas are primarily affected at the onset of the first schizophrenic episode.

Alpha activity decreases during the perception of Necker cube reversals: an application of wavelet transform.

Since the first observation of perceptual reversal by Necker, many theoretical approaches have been proposed. In a previous study, we showed that a positive wave appeared approximately 250 ms prior to the button press of the subjects, indicating perceptual reversal during the observation of the Necker cube figure. A basic difficulty in this type of study is the possible jitter in the latency of the button press due to the variability of the subjects' reaction time during a recording session.

Analysis of the electroencephalographic activity during the Necker cube reversals by means of the wavelet transform.

In previous studies, a perceptual switching related potential was obtained during the observation of a multistable dynamic reversal pattern, where the averaging of the single responses was triggered by subjects pressing a button. The present methodological study aims to increase the signal quality of perceptual switching related potentials considering the dependence of the measurement method on the reaction time of the subject, which may vary significantly during a session, leading to low-amplitude waveform in the averaged event-related-potential (ERP). To overcome this problem in measuring the electrophysiological correlate of an internal event, a pattern selection method based on the wavelet transform (WT) is proposed to choose a subset of single ERPs with more homogenous latencies.

Time-frequency analysis reveals multiple functional components during oddball P300.

A time-frequency decomposition was applied to rare target and frequent non-target event-related potentials (ERPs) elicited in an oddball condition to assess whether multiple functional components occur in the P300 latency range. The wavelet transform (WT) was used because it allows capture of simultaneous or partly overlapping components in ERPs without loosing their temporal relationships. The application of a four-octave quadratic B-spline wavelet transform at the level of single-sweep data allowed us to obtain new information and revealed the presence of separate events during P300 development.

Dynamic properties of the responses to fast omitted stimulus potential paradigm in human.

Visual evoked potentials (VEPs) and omitted stimulus potentials (OSPs) were analyzed on scalp recordings of 10 healthy subjects. OSP responses, obtained after the due-time of the first omitted stimulus at the end of a conditioning stimulus train have been studied mostly in animals. Two types of visual OSP responses were observed in the previous studies: slow (< or = 2 Hz) and fast (> or = 5 Hz).