Publications by authors named "Ummihan Isoglu-Alkac"
Pathog Glob Health
May 2022
Article Synopsis
- The study investigates gene polymorphisms in COVID-19 patients with lung involvement who initially tested negative for the virus using PCR.
- It includes 79 COVID-19 patients and 100 healthy controls, revealing that specific gene variations (AB genotype) were more common in PCR-positive patients compared to those who tested negative but had lung issues.
- The absence of the AB genotype significantly increases the risk of detecting lung involvement through CT scans, suggesting its potential use for early identification of affected individuals despite negative PCR results.
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Curr Med Sci
December 2021
Article Synopsis
- - This study investigates the role of the Circadian Clock Protein PERIOD 3 (PER3) in COVID-19 patients, examining how its gene polymorphisms relate to immune response and circadian rhythm disturbances.
- - Researchers analyzed 200 COVID-19 patients and 100 healthy controls, finding no significant differences in gene polymorphisms overall, but noted a higher prevalence of the 4R/5R genotype among patients who experienced worse outcomes.
- - The results suggest that the 4R/5R genotype may be linked to increased risk of severe illness and mortality in COVID-19, paving the way for further research in this area.
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