Effect of Ketoprofen on acute phase protein concentrations in goats undergoing castration.

Background: The objective of this study was to determine the effect of ketoprofen on acute phase protein (APPs) concentrations in goats undergoing castration. A total of 16 clinically healthy, male and 12 months old goats were enrolled and each case received ketoprofen (group I) or control (group II) in a randomized fashion. Goats were sedated with Xylazine-HCl, afterwards ketoprofen (3 mg/kg) was injected via jugular vein in group I, whereas physiological saline solution was administered to group II.

The effect of surgery (Ovariohysterectomy) on the plasma disposition of meloxicam following intravenous administration in dogs.

Background: Meloxicam (MLX) is a nonsteroidal anti-inflammatory drug used in the relief of postoperative pain for human and veterinary medicine. This study was designed to investigate the effect of surgery on the plasma disposition of MLX in dogs undergoing ovariohysterectomy following a single intravenous injection at a dose of 0.2 mg/kg bodyweight.

The effects of lycopene on DNA damage and oxidative stress on indomethacin-induced gastric ulcer in rats.

Background And Aims: Lycopene, the main antioxidant compound present in tomatoes, has high singlet oxygen- and peroxyl radicals-quenching ability, resulting in protection against oxidative damage in aerobic cell. Indomethacin is a nonsteroidal anti-inflammatory drug, and can promote oxidative damage in gastric tissue. The aim of this study was to investigate the protective effects of lycopene on an indomethacin-induced gastric ulcer model.

Effects of carprofen and meloxicam on C-reactive protein, ceruloplasmin, and fibrinogen concentrations in dogs undergoing ovariohysterectomy.

Objective: To evaluate the effects of perioperative oral administration of carprofen and meloxicam on concentrations of 3 acute-phase proteins in dogs undergoing elective ovariohysterectomy (OVH).

Animals: 18 healthy adult anestrous female dogs undergoing elective OVH.

Procedures: Dogs were allocated to 3 groups (6 dogs/group).

The effect of fasting on the plasma disposition of triclabendazole following oral administration in goats.

This study was designed to investigate the effect of feeding on the plasma disposition of triclabendazole (TCBZ) in goats following oral administration. A total of eight goats, aged 14-16 months and weighing 20-30 kg were used in this study. The animals were allocated into two groups (fasted and fed groups) of four animals each.

The effect of diet type on the plasma disposition of triclabendazole in goats.

The effect of two different diet types (concentrate feed+hay and grazing) on the pharmacokinetic profiles of triclabendazole following oral administration in goats was investigated. A total of 12 goats were randomly allocated into two groups which were either indoor and fed concentrate + hay ration (housed group) or were grazing on pasture (grazing group). Triclabendazole was administered orally to animals in two groups at 10 mg/kg bodyweight.

Comparative plasma dispositions of ivermectin and doramectin following subcutaneous and oral administration in dogs.

This study evaluates the comparative plasma dispositions of ivermectin (IVM) and doramectin (DRM) following oral and subcutaneous administration (200 microg/kg) over a 40-day period in dogs. Twenty bitches were allocated by weight in to four groups (Groups I-IV) of five animals each. Animals in the first two groups (Groups I and II) received orally the injectable solutions of IVM and DRM, respectively, at the dose of 200 microg/kg bodyweight.