(L.) Schott ethanolic leaf extract and fractions exhibited profound anti-inflammatory activity.

Objective: (mas) (L.) Schott, (Dryopteridaceae) is used in traditional medicine, particularly in the Southern parts of Nigeria for the treatment of inflammation, rheumatoid arthritis, wounds and ulcers. In this study, we evaluated the anti-inflammatory activity of its ethanolic leaf extract and fractions.

Bioactive chemical constituents of Duboscia macrocarpa Bocq., and X-ray diffraction study of 11β, 12β-epoxyfriedours-14-en-3α-ol.

A new γ-lactone triterpenoid, Evodoulolide (1) and a new triterpenoid Duboscic acid B (2), along with five known compounds, maslinic acid (3), arboreic acid (4), (E)-3-(4-hydroxyphenyl)-N-[2-(4-hydroxyphenyl) ethyl] prop-2-enamide (5), (E)-heptacos-19-enoic acid (6) and 11β,12β-epoxyfriedours-14-en-3α-ol (7) were isolated from the trunk wood of Duboscia macrocarpa. Their structures were elucidated from extensive D- and D-NMR and MS and by comparison of their spectra with published data. Compounds 1, 3, 5 and 6 exhibited significant α-glucosidase inhibitory activity.

and antioxidant potentials of leaf extract, fractions and isolated bioactive compounds.

Objective: leaves are widely used in ethnomedicine for the management of immuno-inflammatory disorders. We investigated the and antioxidant activity of the leaf extract, fractions and isolated compounds of .

Materials And Methods: The ethyl acetate fraction of the methanol leaf extract was subjected to several chromatographic separations to isolate compounds 1-4.