Publications by authors named "Umberto Occhiuzzi"
Article Synopsis
- The study investigates the effects of low- and high-dose rosuvastatin on the expression of two important proteins, ABCA1 and ABCG1, which help reduce cholesterol in atherosclerotic plaques in patients with severe carotid artery stenosis.
- Results showed that both doses of rosuvastatin led to lower levels of ABCA1 mRNA, but unexpectedly, high-dose treatment increased ABCA1 protein levels while having no significant effect on ABCG1 protein.
- The findings suggest that high-dose rosuvastatin might enhance ABCA1 protein in a way that is independent of changes in cholesterol levels, possibly involving regulation by the microRNA miR-33b-5
Background: Anti-tissue transglutaminase (anti-tTG) and endomysium antibodies (EMA) are detectable in duodenal culture media of celiac disease (CD) patients. To improve the management of this organ culture system, we evaluated the anti-tTG occurrence by immunochromatographic assay (ICA).
Methods: A total of 103 CD patients and 41 disease controls underwent duodenal biopsy for the organ culture.