Publications by authors named "Umberto De Laurentiis"
Objective: In endometrial carcinoma patients, sentinel lymph node bilateral mapping fails in 20-25% of cases, with several factors affecting the likelihood of detection. However, pooled data about predictive factors of failure are lacking. The aim of this systematic review and meta-analysis was to assess the predictive factors of sentinel lymph node failed mapping in endometrial cancer patients undergoing sentinel lymph node biopsy.
View Article and Find Full Text PDFArticle Synopsis
- Endometrial cancer arising in adenomyosis (EC-AIA) is a rare and challenging uterine disease with malignant transformations often occurring in menopausal women.
- The study reviewed existing literature from 2002 to 2022, analyzing 37 cases found in case reports and series, highlighting that EC-AIA shares symptoms with regular endometrial cancer but is more difficult to diagnose preoperatively.
- Key findings indicate EC-AIA has a higher prevalence of non-endometrioid histotypes and advanced cancer stages, leading to a worse prognosis, emphasizing the need for more extensive future research to better understand this condition.
Endometrial cancer (EC) is the most common gynecological neoplasm in high-income countries. Five-year survival rates are related to stage at diagnosis, but currently, no validated screening tests are available in clinical practice. The metabolome offers an unprecedented overview of the molecules underlying EC.
View Article and Find Full Text PDFLaparoscopic entry techniques: Which should you prefer?
Int J Gynaecol Obstet
March 2023
Background: Despite a debate spanning two decades, no consensus has been achieved about the safest laparoscopic entry technique.
Objectives: To update the evidence about the safety of the main different laparoscopic entry techniques.
Search Strategy: Six electronic databases were searched from inception to February 2021.