Potential Target Metabolites From Gut Microbiota Against Hepatocellular Carcinoma: A Network Pharmacology and Molecular Docking Study.

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, posing significant challenges and economic burdens on healthcare systems. Gut microbiota metabolites have shown promise in cancer treatment, but the specific active metabolites and their key targets remain unclear. This study employed a network pharmacology-based approach to identify potent metabolites of gut microbiota and their key targets.

Cultivating sustainable environmental performance: The role of green talent management, transformational leadership, and employee engagement with green initiatives.

Background: The success of organizations' sustainable performance mainly depends on their human resource capital and for this organizations now need to focus on green human capital development programs including green talent management (GTM). GTM entails attracting, nurturing, and retaining those people who can promote the green initiatives of the organization.

Objective: This paper aims to investigate the impact of GTM, transformational leadership, and employee engagement on the sustainable environmental performance of organizations.

Posthumous Organ Donation Decision: The Role of Empathy and Knowledge on the Attitude and Willingness to Donate among University Students in Pakistan.

Organ transplantation is a common procedure in many countries, but it can still be hampered by a lack of donors. Many reasons exist for people's hesitation to sign the donor card and this study explores the factors affecting posthumous organ donations motivation. The objectives of the study were to examine the role of knowledge, empathy, and attitude toward willingness to donate in posthumous organ donation decisions.

Influence of supply chain risk management and its mediating role on supply chain performance: perspectives from an agri-fresh produce.

As agropreneurs of fresh fruits and vegetables are important contributors to the economy, supply chain risk management is vital for their survival and growth. Therefore, this study examined the mediating effect of supply chain risk management in reducing the impact of supply chain risks and increasing supply chain performance among small scale agropreneurs in Malaysia. It also evaluated the moderating role that knowledge management plays between supply chain risks and supply chain risk management.

In-Vitro Assessment Of The Therapeutic Potential Of Polymyxins And Tigecycline Against Multidrugresistant Acinetobacter Isolates From Infected Wounds.

Background: The incidence of multidrug-resistant (MDR), extreme drug resistant (XDR), and pan drug-resistant (PDR) Acinetobacter are increasing throughout the world. The therapeutic management and control of Acinetobacter are difficult due to the emergence of drug resistance and its enduring capacity to survive in the environment. The present study was designed to appraise the efficacy of Polymyxins and Tigecycline against multidrugresistant Acinetobacter isolates from surgical and burn wounds.