Objective: Data extraction from the published literature is the most laborious step in conducting living systematic reviews (LSRs). We aim to build a generalizable, automated data extraction workflow leveraging large language models (LLMs) that mimics the real-world 2-reviewer process.
Materials And Methods: A dataset of 10 trials (22 publications) from a published LSR was used, focusing on 23 variables related to trial, population, and outcomes data.
Objective: Data extraction from the published literature is the most laborious step in conducting living systematic reviews (LSRs). We aim to build a generalizable, automated data extraction workflow leveraging large language models (LLMs) that mimics the real-world two-reviewer process.
Materials And Methods: A dataset of 10 clinical trials (22 publications) from a published LSR was used, focusing on 23 variables related to trial, population, and outcomes data.
High throughput protein-protein interaction (PPI) profiling and computational techniques have resulted in generating a large amount of PPI network data. The study of PPI networks helps in understanding the biological processes of the proteins. The comparative study of the PPI networks helps in identifying the conserved interactions across the species.
View Article and Find Full Text PDFMotivation: The advancement of high-throughput PPI profiling techniques results in generating a large amount of PPI data. The alignment of the PPI networks uncovers the relationship between the species that can help understand the biological systems. The comparative study reveals the conserved biological interactions of the proteins across the species.
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October 2021
The growing use of electronic health records in the medical domain results in generating a large amount of medical data that is stored in the form of clinical notes. These clinical notes are enriched with clinical entities like disease, treatment, tests, drugs, genes, and proteins. The extraction of clinical entities from clinical notes is a challenging task as clinical notes are written in the form of natural language.
View Article and Find Full Text PDFBackground: High throughput experiments have generated a significantly large amount of protein interaction data, which is being used to study protein networks. Studying complete protein networks can reveal more insight about healthy/disease states than studying proteins in isolation. Similarly, a comparative study of protein-protein interaction (PPI) networks of different species reveals important insights which may help in disease analysis and drug design.
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