Publications by authors named "Uma Shrestha"
Background: Child birth related fear and low self-efficacy for child birth found common among primiparous women. Antenatal group psycho-educational interventions have been used as important strategies to address child birth fear and self-efficacy. Thus, this study aimed to find out the status of child birth fear among antenatal women and effect of group psycho-educational interventions among primiparous women.
View Article and Find Full Text PDFNepal exhibits a tuberculosis (TB) incidence rate that is comparable to neighbouring high TB incidence countries. In addition, it records >500 cases of multi-drug resistant (MDR) TB each year. The objective of this study was to perform whole-genome bioinformatic analysis on MDR-TB isolates from Nepal (n = 19) to identify the specific mutations underlying their phenotypic resistance.
View Article and Find Full Text PDFArticle Synopsis
- Extensively drug-resistant tuberculosis (XDR-TB) presents significant treatment challenges in countries like Nepal.
- Researchers have sequenced the genome of an XDR-TB strain from Nepal for the first time.
- The study identifies specific single-nucleotide variations in the genome linked to the bacteria's extensive drug resistance.
Objectives: The objective of the study was to assess the differences of iodine status as measured by urinary iodine excretion (UIE) between cases of hypothyroidism and healthy controls.
Materials And Methods: The study was conducted in cases with subclinical hypothyroidism ( = 58) and overt hypothyroidism ( = 41) and compared with age- and sex-matched healthy euthyroid controls ( = 52) attending Universal College of Medical Sciences Teaching Hospital, Bhairahawa, Nepal. Serum free triiodothyronine (fT), free thyroxine (fT), and thyroid-stimulating hormone (TSH) were estimated by competitive ELISA and sandwich ELISA, respectively (Diametra, Italy).