Neurolymphomatosis in Primary Cutaneous CD4+ Pleomorphic Small/Medium-sized T-cell Lymphoma Mimicking Hansen's Disease.

Neurolymphomatosis (NL) refers to nerve infiltration by neurotropic neoplastic cells in the setting of a known or an unknown hematological malignancy. It typically presents as painful or painless peripheral mononeuropathy, mononeuritis multiplex, polyneuropathy, polyradiculopathy, or cranial neuropathy. A 32-year-old male presented with a hyperpigmented hypoesthetic plaque over the anterolateral aspect of the right leg with thickening of the right common peroneal nerve and foot drop clinically diagnosed as Hansen's disease.

Multifaceted adult T-cell leukemia/lymphoma in India: a case series.

Background: Adult T-cell leukemia/lymphoma (ATL) is caused by human T-cell lymphotropic virus type-1 (HTLV-1). India is considered as a nonendemic region for HTLV-1. Recent upsurge of cases have been noted in southern parts of India.

Severe cutaneous adverse drug reactions: a clinicoepidemiological study.

Background: Drug eruptions range from transient erythema to the life threatening severe cutaneous adverse reactions (SCAR) that encompass Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) and drug reaction with eosinophilia and systemic symptoms complex (DRESS).

Aims And Objectives: To study the clinical and epidemiological aspects of cutaneous adverse drug reactions (CADR).

Materials And Methods: Ethical clearance was obtained from the institutional ethics committee.

Malignant pyoderma gangrenosum eroding the parotid gland successfully treated with dexamethasone pulse therapy.

Background: Malignant pyoderma gangrenosum is a rare ulcerative variant of pyoderma gangrenosum (PG) involving the head and neck. Early intervention is crucial to prevent an aggressive outcome.

Objectives: We report a patient with malignant PG eroding into the parotid gland treated with dexamethasone pulse therapy.

Drug reaction with eosinophilia and systemic symptoms: observations from a tertiary care institution.

Background: Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe drug reaction which can mimic a viral infection, an autoimmune disease or a neoplastic disease.

Aims: To study the clinical and epidemiological aspects of DRESS and to identify the precipitating drugs.

Methods: All patients admitted to the dermatology ward of our tertiary care hospital from 1 st October 2010 to 30 th September 2013 with probable or definite DRESS as per the RegiSCAR scoring system were included in this prospective study.

Syphilis of Fungal world: Novel Skin Manifestations of Histoplasmosis in an Immunocompetent Host.

A case of chronic disseminated cutaneous histoplasmosis with unusual skin manifestations in an immunocompetent host is reported. Presence of cutaneous ulcers, linear erythematous plaques, skin coloured atrophic plaques and recurrent self-limiting oral ulcers in a single patient has not been documented in literature so far. Diagnosis was established by identifying small intracellular yeast-like cells of Histoplasma in tissue smear and skin biopsy.

Adult T-cell leukemia/lymphoma: a retroviral malady.

Adult T-cell leukemia/lymphoma (ATLL) is an aggressive leukemia/lymphoma of mature T-lymphocytes caused by human T-cell lymphotropic virus type 1 (HTLV-1). At a tertiary healthcare center in South India, a 58-year-old female presented with multiple erythematous, crusted, and umbilicated papules over the body along with cervical lymphadenopathy. The skin biopsy was consistent with cutaneous T-cell lymphoma.

Postpartum pemphigoid gestationis.

Pemphigoid gestationis (PG) or herpes gestationis is a rare autoimmune subepidermal blistering disorder associated with pregnancy. The condition typically develops during the second or third trimester of pregnancy, but has been rarely reported in the first trimester and postpartum period. Here, we report a case of PG that presented for the first time in the postpartum period, associated with a low birth weight baby.

Localized psoriasis herpeticum: Case report and review of literature.

Kaposi's varicelliform eruption (KVE) is a widespread cutaneous eruption caused by viruses, especially herpes simplex virus in patients with pre-existing dermatoses. "Psoriasis herpeticum" refers to the rare occurrence of KVE in patients with psoriasis. We report a case of KVE localized to the face in a patient with exfoliative dermatitis secondary to psoriasis.

Purpuric macules with vesiculobullous lesions: a novel manifestation of Chikungunya.

Background: Chikungunya (CHIK) is an emerging viral disease with a myriad of cutaneous manifestations.

Aims: The aim of our study was to document the morphology and evolution of skin lesions in cases presenting with fever, purpuric macules and vesiculobullous lesions, to confirm its causative relationship with CHIK, and to investigate further in order to delineate possible mechanisms of bulla formation in these cases.

Materials And Methods: A prospective, descriptive hospital-based study was carried out at a tertiary health care centre in Kerala.

Sub-polar lepromatous leprosy localized to the face.

Leprosy is an infectious disease characterized by a wide spectrum of clinical manifestations, ranging from tuberculoid to lepromatous disease with immunologically unstable borderline forms in between. In clinical practice cases often do not conform to a classical textbook description, which may lead to misdiagnosis if not properly investigated. A 22-year-old patient presented to us with erythematous plaques localized to the face.

Idiopathic scoliosis in Singapore schoolchildren: a prevalence study 15 years into the screening program.

Study Design: A point prevalence survey of 72,699 schoolchildren in four age groups was performed.

Objectives: To determine the prevalence rates of idiopathic scoliosis and to compare with a previous prevalence study done 15 years earlier.

Summary Of Background Data: Prevalence rates for idiopathic scoliosis of 5 degrees or more in schoolchildren were established in a study performed in 1982.

A randomized trial of rigid gas permeable contact lenses to reduce progression of children's myopia.

Purpose: To test whether rigid gas permeable (RGP) contact lens wear can reduced the rate of myopia progression in school age children.

Design: Randomized clinical trial.

Setting: Single clinical center.