Consecutive oxidative stress in CATALASE2-deficient Arabidopsis negatively regulates Glycolate Oxidase1 activity through S-nitrosylation.

Glycolate oxidase (GOX) is a crucial enzyme of photorespiration involving carbon metabolism and stress responses. It is poorly understood, however, how its activities are modulated in response to oxidative stress elicited by various environmental cues. Analysis of Arabidopsis catalase-defective mutant cat2 revealed that the GOX activities were gradually repressed during the growth, which were accompanied by decreased salicylic acid (SA)-dependent cell death, suggesting photorespiratory HO may entrain negative feedback regulation of GOX in an age-dependent manner.

The Key Targets of NO-Mediated Post-Translation Modification (PTM) Highlighting the Dynamic Metabolism of ROS and RNS in Peroxisomes.

Nitric oxide (NO) has been firmly established as a key signaling molecule in plants, playing a significant role in regulating growth, development and stress responses. Given the imperative of sustainable agriculture and the urgent need to meet the escalating global demand for food, it is imperative to safeguard crop plants from the effects of climate fluctuations. Plants respond to environmental challenges by producing redox molecules, including reactive oxygen species (ROS) and reactive nitrogen species (RNS), which regulate cellular, physiological, and molecular processes.