The Pxmp2 and PoleI genes are linked by a bidirectional promoter in an evolutionary conserved fashion.

Pxmp2 is the most abundant peroxisomal membrane protein in higher eukaryotes. Its expression is tissue-specific with highest levels of expression in liver, kidney and heart tissue. We have analysed the 5'-flanking genomic region of the murine Pxmp2 gene and we found, that the first exon of the gene encoding the DNA polymerase epsilon (PoleI) was localized adjacent to the first exon of the Pxmp2 gene in head to head orientation.

Murine calmodulin binding protein 1 (Calmbp1): tissue-specific expression during development and in adult tissues.

Expression of the 1.9 kb cDNA of murine Calmbp1 has been shown to interfere with the mitotic S-M checkpoint in yeast (J. Cell Sci.