Publications by authors named "Ulrike Reid"
Article Synopsis
- The pathophysiology of heparin-induced thrombocytopenia (HIT) is linked to antibodies that target heparin-platelet factor 4 complexes, leading to platelet activation.
- A study involving 600 patients undergoing hip and knee surgeries showed that both unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH) treatments led to an increase in these antibodies.
- However, the LMWH (clivarin) showed significantly lower levels of functional antibodies compared to UFH, indicating a decreased risk of platelet activation and thrombocytopenia in those treated with clivarin.
