Publications by authors named "Ulrike Irmgard Attenberger"

To report results of interventional treatment of refractory non-traumatic abdomino-thoracic chylous effusions in patients with lymphoproliferative disorders. 17 patients (10 male; mean age 66.7 years) with lymphoproliferative disorders suffered from non-traumatic chylous effusions (chylothorax n = 11, chylous ascites n = 3, combined abdomino-thoracic effusion n = 3) refractory to chemotherapy and conservative therapy.

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Purpose: Due to a lack of data, there is an ongoing debate regarding the optimal frontline interventional therapy for unresectable hepatocellular carcinoma (HCC). The aim of the study is to compare the results of transarterial radioembolization (TARE) as the first-line therapy and as a subsequent therapy following prior transarterial chemoembolization (TACE) in these patients.

Methods: A total of 83 patients were evaluated, with 38 patients having undergone at least one TACE session prior to TARE [27 male; mean age 67.

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Article Synopsis
  • Image-based detection of intralesional fat in liver lesions is important for diagnosing hepatocellular carcinoma (HCC) and correlates with better prognosis, prompting this study to examine the link between fat content and tumor grade in steatotic HCCs.
  • The study analyzed 57 patients with steatotic HCC, finding that higher intralesional fat content in well-differentiated (G1) tumors compared to less-differentiated (G2 and G3) tumors, indicating that fat quantification could help differentiate tumor grades.
  • The use of MRI proton density fat fraction (PDFF) mapping proved effective in distinguishing between different grades of HCC, suggesting its potential role in enhancing precision medicine for tumor
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  • A study looked at 10 patients with swelling in their necks that kept coming back and didn't have a clear cause.
  • They found that most of the swelling was on the left side, and all patients had problems with their lymphatic system that were causing the swelling.
  • After treatment, 6 out of 10 patients felt completely better, while 1 felt partially better, but 3 still have some swelling and don't want more treatment.
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Objective: High spatial and temporal resolution contrast-enhanced magnetic resonance angiography (MRA) with gadolinium-based contrast agents (GBCAs) at standard dose offers both detailed anatomic information on both arterial and venous vessels and hemodynamic characteristics. Several preclinical and clinical dynamic 3-dimensional (3D) MRA studies that focused on arterial vessels only proposed that high image quality may also be achieved with significantly reduced GBCA doses, calling into question the need to use standard doses. A systematic analysis of GBCA doses and resulting image quality for both arteries and veins has not yet been performed.

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Due to its excellent intrinsic soft tissue contrast, magnetic resonance imaging allows excellent visualization and anatomical separation of therapy-relevant risk structures such as the mesorectal fascia, local lymph nodes, and vascular structures in patients with rectal carcinoma. This makes magnetic resonance imaging (MRI) a valuable evaluation method for further therapeutic stratification. In particular, MRI is indispensable for the decision to refrain from neoadjuvant therapy and to choose a primary surgical approach.

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Background:  Diffusion-weighted imaging (DWI) is an essential component of the multiparametric MRI exam for the diagnosis and assessment of prostate cancer (PCa). Over the last two decades, various models have been developed to quantitatively correlate the DWI signal with microstructural characteristics of prostate tissue. The simplest approach (ADC: apparent diffusion coefficient) - currently established as the clinical standard - describes monoexponential decay of the DWI signal.

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Personalized precision medicine requires highly accurate diagnostics. While radiological research has focused on scanner and sequence technologies in recent decades, applications of artificial intelligence are increasingly attracting scientific interest as they could substantially expand the possibility of objective quantification and diagnostic or prognostic use of image information.In this context, the term "radiomics" describes the extraction of quantitative features from imaging data such as those obtained from computed tomography or magnetic resonance imaging examinations.

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