Rb and [O]HO myocardial perfusion PET imaging: a prospective head to head comparison.

Background: Rb PET and [O]HO PET are both validated tracers for myocardical perfusion imaging but have not previously been compared clinically. During our site's transition from Rb to [O]HO PET, we performed a head-to-head comparison in a mixed population with suspected ischemic heart disease.

Methods: A total of 37 patients referred for perfusion imaging due to suspicion of coronary stenosis were examined with both Rb and [O]HO PET on the same day in rest and during adenosine-induced stress.

Myocardial Flow Reserve, an Independent Prognostic Marker of All-Cause Mortality Assessed by Rb PET Myocardial Perfusion Imaging: A Danish Multicenter Study.

Background: Rubidium-82 positron emission tomography (Rb PET) myocardial perfusion imaging is used in clinical practice to quantify regional perfusion defects. Additionally, Rb PET provides a measure of absolute myocardial flow reserve (MFR), describing the vasculature state of health. We assessed whether Rb PET-derived MFR is associated with all-cause mortality independently of the extent of perfusion defects.

Coronary Microvascular Disease Assessed by 82-Rubidium Positron Emission Tomography Myocardial Perfusion Imaging Is Associated With Small Vessel Disease of the Kidney and Brain.

Background Coronary microvascular disease (CMD) may be part of a systemic small vessel disease that also manifests as neurological impairment and kidney disease. However, clinical evidence supporting a potential link is scarce. We assessed whether CMD is associated with an increased risk of small vessel disease in the kidney and brain.

Prognostic implications of myocardial perfusion imaging by 82-rubidium positron emission tomography in male and female patients with angina and no perfusion defects.

Aims: Myocardial perfusion imaging with 82-rubidium positron emission tomography (82Rb-PET) is increasingly used to assess stable coronary artery disease (CAD). We aimed to evaluate the prognostic value of 82Rb-PET-derived parameters in patients with symptoms suggestive of CAD but no significant reversible or irreversible perfusion defects.

Methods And Results: Among 3726 consecutive patients suspected of stable CAD who underwent 82Rb-PET between January 2018 and August 2020, 2175 had no regional perfusion defects.

[Insufficient blood pressure control following coronary revascularization].

Introduction: After coronary revascularization, anti-angina treatment is often withdrawn or reduced while the ejection fraction tends to improve. Both contribute to increase blood pressure (BP). The purpose of the present study was to evaluate BP control in patients after revascularization procedures.

Isolated systolic hypertension in an elderly Danish population. Prevalence and daytime ambulatory blood pressure.

Isolated systolic hypertension (ISH) is a major risk factor for cardiovascular complications. Nevertheless, data on the prevalence in a representative population do not seem to be available. The prevalence of ISH and the white coat effect was thus studied in a cross-sectional survey of 2806 inhabitants aged 70-80 years.

Increased systolic ambulatory blood pressure and microalbuminuria in treated and non-treated hypertensive smokers.

Objective: The primary aim of the present study was to evaluate the impact of smoking status on both clinic and ambulatory blood pressure (BP) and heart rate (HR) by using 24-h ambulatory BP monitoring in treated and non-treated hypertensive smokers and non-smokers. A secondary aim was to evaluate the interrelations between BP, smoking status and microalbuminuria.

Design: Five hundred and eighty treated and non-treated hypertensive smokers and non-smokers were consecutively recruited.

Effects of supine, prone, and lateral positions on cardiovascular and renal variables in humans.

The hypothesis was tested that changing the direction of the transverse gravitational stress in horizontal humans modulates cardiovascular and renal variables. On different study days, 14 healthy males were placed for 6 h in either the horizontal supine or prone position following 3 h of being supine. Eight of the subjects were in addition investigated in the horizontal left lateral position.