Effects of the highly COX-2-selective analgesic NSAID etoricoxib on the rate of orthodontic tooth movement and cranial growth.

Background: NSAID analgesics have found widespread use in the treatment of pain, inflammation and fever. The highly COX-2-selective NSAID etoricoxib has shown a favorable side effect profile and excellent analgesic efficacy, particularly for dental and orthodontic pain, surpassing the current standard analgesic in orthodontics, acetaminophen. However, potential side effects on the rate of orthodontic tooth movement (OTM) and cranial growth, relevant for clinical usability during orthodontic treatment, have not yet been investigated.

Impact of radiotherapy on implant-based prosthetic rehabilitation in patients with head and neck cancer: A prospective observational study on implant survival and quality of life-Preliminary results.

Purpose: To study implant-based prosthetic rehabilitation of head and neck cancer patients with focus on implant survival and quality of life.

Materials And Methods: The prospective observational study presents preliminary results of 29 edentulous head neck cancer patients (20 patients after radiotherapy) with 165 OsseoSpeed implants. Implant success after 1-year follow-up was evaluated by means of the Albrektsson criteria.

Can dental panoramic radiographic findings serve as indicators for the development of medication-related osteonecrosis of the jaw?

Objectives: The purpose of this case-control study was to find a correlation between certain imaging findings in dental panoramic radiographs and the risk for developing a medication-related osteonecrosis of the jaw (MRONJ) in patients taking antiresorptive therapy (AT).

Methods: Randomized and blinded dental panoramic radiographs of 60 patients undergoing antiresorptive drug treatment (36 patients with MRONJ, 24 patients without MRONJ) and of 60 patients without AT were analyzed by 3 experts for the following signs: sequestrum, osteosclerosis, difference in sclerosing of alveolar process and body of mandible, visible alveolar socket, enhancement and loss of lamina dura, enhancement of the oblique ridge, enhancement of the mandibular canal, proliferative periostitis and osteolytic processes at the cortex.

Results: Signs were seen significantly more often in patients undergoing AT than in the control group (CG) (osteosclerosis p-value = 0.

Strontium ranelate improved tooth anchorage and reduced root resorption in orthodontic treatment of rats.

The anchorage mechanisms currently used in orthodontic treatment have various disadvantages. The objective of this study was to determine the applicability of the osteoporosis medication strontium ranelate in pharmacologically induced orthodontic tooth anchorage. In 48 male Wistar rats, a constant orthodontic force of 0.

Differentiated analysis of orthodontic tooth movement in rats with an improved rat model and three-dimensional imaging.

Rat models currently available for analysis of orthodontic tooth movement often lack differentiated, reliable and precise measurement systems allowing researchers to separately investigate the individual contribution of tooth tipping, body translation and root torque to overall displacement. Many previously proposed models have serious limitations such as the rather inaccurate analysis of the effects of orthodontic forces on rat incisors. We therefore developed a differentiated measurement system that was used within a rat model with the aim of overcoming the limitations of previous studies.

Implant-supported fixed dental prostheses in an edentulous patient with dystrophic epidermolysis bullosa.

Purpose: This clinical report describes the use of implant-supported fixed dental prostheses (ISFDPs) in a severe case of dystrophic epidermolysis bullosa.

Materials And Methods: The patient's appearance was characterized by reduced corporal growth and severe mutilation of the hands and feet. He was first examined at age 20.

Primary stability of a conical implant and a hybrid, cylindric screw-type implant in vitro.

Purpose: The differences with respect to primary stability between 2 Camlog implants, a conical implant, and a hybrid cylindric screw-type implant, were investigated in vitro. The effect of underdimensioned implant bed preparation was also studied for both implant designs.

Materials And Methods: In an in vitro model the stability of different implants in fresh porcine iliac bone blocks was measured using torque moment values, the Periotest, resonance frequency analysis, and push-out testing.

Reconstruction of mandibular defects following tumor ablation by vertical distraction osteogenesis using intraosseous distraction devices.

Objectives: Distraction osteogenesis has recently evolved a challenging technique to overcome major drawbacks of conventional augmentation procedures. We, therefore, report the application of miniaturized intraosseous distraction devices for the rehabilitation of mandibular defects due to ablative tumor surgery.

Methods: In 10 patients who had undergone box-shaped or segmental resections, augmentation of the residual mandibular bone or of full thickness iliac crest grafts was performed by intraosseous implant-shaped distractors.

The use of implant-supported prostheses in the functional and psychosocial rehabilitation of tumor patients.

Purpose: The present study investigated the residual functional constraints as well as the psychosocial rehabilitation of tumor patients following prosthetic treatment with implant-supported dentures.

Materials And Methods: A clinical examination and semistructured interview were performed in 66 of 132 consecutive patients who underwent tumor resection and subsequent implant-supported restoration between 1985 and 1997.

Results: Functional and psychosocial constraints were improved by between 91% (general comfort) and 47% (social reintegration) of all cases, but these constraints were never fully compensated for.