Advanced glycation end-products in anterior chamber aqueous of cataractous patients.

Purpose: To investigate whether the advanced glycation end-products (AGEs) pentosidine, N( epsilon )-(carboxymethyl)lysine (CML), and imidazolone are present in the aqueous of cataract patients and how AGE levels correlate to cataract type or the diabetic condition of the patient.

Setting: Departments of Ophthalmology and Internal Medicine, University of Jena, Jena, Germany.

Methods: Aqueous and serum samples from 77 cataractous patients (33 nondiabetics, 44 diabetics; 14 with dense posterior, 63 with nuclear cataracts) were investigated.