Walking Bike as an Effective Tool to Reduce Plantar Peak Pressure in Diabetes Mellitus.

Background: Foot ulcers and infections are a major and costly problem in patients with diabetes and a major cause of amputations. Plantar peak pressure plays an essential role in plantar ulceration. Off-loading is a common tool to reduce plantar peak pressure and risk of ulceration.

[Does inflammatory activity of Charcot foot affect successful corrective arthrodesis?].

Background: Neuro-osteoarthropathy of the foot (CN) is divided into an active and inactive stage, with impact on the further treatment. The histopathological Charcot score (HCS) can be used, to grade the inflammatory activity in tissue samples.

Research Question: This study aims to clarify whether successful bony healing after arthrodesis is related to inflammatory activity of the disease.

Histopathological assessment of a two-stage reconstructive procedure of the infected Charcot foot.

Introduction: Charcot neuropathic osteoarthropathy (CN) can be complicated by osteomyelitis (OM). Surgery is a standard procedure to treat OM including debridement and interposition of antibiotic-loaded cement (ABLC) spacer. The course of CN and OM was investigated on a histopathological level.

[Histopathological Charcot score on intraoperative tissue samples from the foot : A prospective investigation].

Background: Charcot neuropathy is a severe complication in patients with neuropathy. Without treatment, CN can lead to a destruction and collapse of the foot, with subsequent ulceration and infection. Finding an early diagnosis is essential and is based on clinical and radiological parameters (X-ray and MRI) because there is still no specific and reliable test.

Clinical benefit and improvement of activity level after reconstruction surgery of Charcot feet using external fixation: 24-months results of 292 feet.

Background: Reconstruction of Charcot feet remains a surgical challenge. The goal of this study was to investigate safety and clinical benefit from reconstruction of Charcot feet using an external fixator. There is limited valid data regarding long-term outcomes for Charcot foot procedures.

Clinical acceptance, reasons for rejection, and reduction of in-shoe peak pressure with interdigital silicone orthoses.

Background: For several years, confectioned or customized interdigital silicone orthoses have been used to treat toe malformations; however, long-term clinical and biomechanical studies are missing. The aim of this study was to evaluate the biomechanical effects of these orthoses and their clinical acceptance.

Methods: In 2008, 46 patients (30 women and 16 men; average age, 56.

Infections with Pseudomonas aeruginosa in Charcot arthropathy of the foot.

Background: Patients with Charcot arthropathy present a high risk for ulcers with secondary bone infection. Infections with Pseudomonas aeruginosa represent a severe threat to the patients. We hypothesized that infections with P aeruginosa result in a longer stay in hospital and more operations than infections with other bacteria.