Assessing mean corpuscular volume as a screening tool for gestational vitamin B12 deficiency based on NHANES.

Vitamin B12 can lead to neurological deficits. We assessed whether the mean corpuscular volume (MCV) could be a sufficiently sensitive measurement for abnormal serum methylmalonic Acid (MMA) and total plasma homocysteine (tHCY) (biomarkers of vitamin B12 or folate deficiency) and if so, at what cutoff value. A total of 26,397 participants (12,730 males and 13,667 females) were included in the analysis.

Examining the relationship between autism spectrum disorder and neural tube defects.

Folate and vitamin B deficiencies have been strongly associated with neural tube defects, preliminary research suggests folate and B deficiency may also be associated with autism spectrum disorder (ASD). We examined the association between neural tube defects and ASD as a further avenue to examine the hypothesis that ASD is related to maternal folate and B deficiency during pregnancy. A retrospective case-control study was performed using the Military Health System Data Repository.

Headache triggers in the US military.

Background: Headaches can be triggered by a variety of factors. Military service members have a high prevalence of headache but the factors triggering headaches in military troops have not been identified.

Objective: The objective of this study is to determine headache triggers in soldiers and military beneficiaries seeking specialty care for headaches.