[The biological kinetics of biofilms of clinical strains of Staphylococcus aureus and Pseudomonas aeruginosa separated from patients with bronchopulmonary complications under traumatic disease of spinal cord].

The capacity and intensity of formation of microbial biofilms was analyzed in 24 strains of Staphylococcus aureus and Pseudomonas aeruginosa in static conditions of cultivation during 24, 48, 72 and 96 yours. The microorganisms were separated from patients with bronchopulmonary infectious complications in acute and early periods of traumatic disease of spinal cord.

[Low-temperature sterilization for the surgical infection prophylaxis].

The comparative characteristic of the accepted methods of low-temperature sterilization of medical equipment is given. Special attention is devoted to the surgical infection prophylaxis. The efficacy, expediency and safety of gas sterilization with ethilenoxide is proved.

[Differential treatment of acute pancreatitis].

Results of examination and treatment of 194 patients with acute pancreatitis were analyzed. It is revealed that the diagnosis of an etiopathogenetic form of acute pancreatitis is a key moment in the choice of the treatment. Patients with acute biliary pancreatitis and alimentary pancreonecrosis with pancreatogenic peritonitis require urgent surgical treatment at early stages of the disease.

[Pathogenetic criteria of nephroptosis].

The aim of the study was to specify treatment policy in nephroptosis on the basis of characteristics of the onset, development and course of the disease. A total of 83 patients with nephroptosis were examined. The rotation angles of the kidney were summed using standard excretory urograms in clino- and orthostasis.

[Reflexotherapy in patients with ischemic angiopathies of the lower extremities].

Comparative assessment of different methods of reflexotherapy - RT (acupuncture, electroacupuncture, pharmacopuncture and the termopuncture) in treatment of ischemic angiopathies of the lower extremities is presented. One hundred and twenty-four patients with ischemic angiopathies were treated, 86 of them had I - II stage of the disease, 38 - III stage. Diagnosis of the disease and assessment of treatment efficacy were based on clinical, laboratory and special instrumental examinations.

[Evaluation of clarithromycin efficacy in the treatment of community-acquired pneumonia on the basis of the Binax NOW test results (a prospective open trial)].

The results of the treatment of community-acquired pneumonia with clarithromycin (500 mg bid for 6-8 days) at 172 patients (military recruits aged 18-25) are presented. Diagnosis, infection performance, treatment efficacy were evaluated by complex of data (X-ray, sputum analysis by bacteriological and cultural tests and immunochromatography test Binax NOW for pneumococcal antigen identification). High efficacy of clarithromycin for the treatment of moderate and mild pneumonia (including pneumococcal pneumonia) was demonstrated.

[Reliability of the sterilization of surgical instruments is a key point in prevention of surgical infection].

Occurrence of postoperative purulent-inflammative complications (PPIC), their structure and dynamics after improvement of sterilization are studied. For epidemiological analysis 65,246 medical histories of operated patients were studied, in 404 of them PPIC were revealed. The PPIC rate reduced from 3.

[The coordination of the work of medical units and institutions in the combat arms and services of the Armed Forces].

The transition to a territorial system of medical support needs to solve a problem of control over the work of all military medical establishments in the zone of responsibility of the base military hospital independently of their subordination to different fighting services. To meet these requirements it is necessary to create a coordination centre (group) in the base military hospital. Its basic task is to coordinate all medico-diagnostical, sanitary-hygienic and counter-epidemic measures in the zone of responsibility and also to supervise the special training of medical personnel.

[A comparative evaluation of different methods of forming a colonic anastomosis in repeat surgical interventions].

The results of repeated operations on the large intestine, mainly reconstructive operations, are analysed. Surgical interventions with the performance of a triangular anastomosis, including that by a method modified by the authors, were carried out on 50 patients. The operative results, particularly those in the last group of patients, are very promising.

[The primary postponed radical surgical treatment of acute suppurative paraproctitis].

The method of primarily postponed radical surgical treatment of acute purulent paraproctitis consists in puncture of the abscess, introduction of a double-channel drain, and continuous drop irrigation of the cavity for 1-2 days with antiseptic solutions and active aspiration for preoperative management. When the inflammatory process abates, fistulochromography is conducted and a radical operation is carried out on the same day with excision of the inner opening of rectal fistula. The method makes it possible to combine two operations in one stage which are undertaken in one third of patients in routine surgical treatment of acute paraproctitis.

[Determination of the viability of a patient's intestine by using laser doppler flowmetry during surgery].

Intraoperative determination of the viability of the intestine by means of laser Doppler flow measurement was conducted in 26 patients. The method proved to be highly effective, made it possible to judge most objectively the degree of changes in blood flow in various parts of the intestine in a short time and correct them subsequently during the operation, and considerably reduced the possibility of the development of postoperative complications due to inadequate appraisal of the degree of vascularization of the mobilized segments of the small and large intestine which are prepared for the formation of the anastomosis.

[Experience in the use of laser instruments in surgery of the anorectal region].

The article discusses experience in surgical treatment of 480 patients with the most common diseases of the anorectal region (acute and chronic haemorrhoids, acute and chronic paraproctitis, polyps, chronic fissures of the anal canal) in which special laser tools were used. The carbonic acid laser Skalpel-1 with a wave length of 10.6 microns and power of 30 W was used as the source of laser radiation.

[Experience in the use of a pneumo-obturator in patients with colostomy].

The authors were able to prevent uncontrollable discharge of intestinal contents in 70 patients with colostomy by means of a pneumo-obturator of an original design. Its advantages over magnetic obturating devices were revealed: the simple and light design, hygienic properties, short adaptation period, and no need for implantation of a foreign body into the tissues surrounding the colostomy. Sixty-four patients use the device regularly and are able to retain feces of any consistency.

[Distribution of aromatic amino acid residues according to the character of their microenvironment and the dynamics of the conformational properties of the protein molecule C1q].

The distribution of aromatic amino acid residues in the Clq molecule according to their microenvironment was studied by the methods of difference thermal and solvent perturbation spectroscopy, fluorescence and chemical modification. Out of the three tryptophan residues located in the globular part of A- chain one residue is completely exposed on the surface, while other two are only partially exposed to a solvent. Chemical modification of tryptophanyls significantly affects the hemolytic activity of Clq, that may evidence for the formation of immunoglobulin-binding sites with participation of A- chains as well as for the location of, at least, one of the three tryptophan residues in A- chain close to the immunoglobulin-binding site or even participation in the formation of the latter.

[Place of carbohydrate antigens in the spectrum of protein tumor markers in patients with tumors at different sites].

Carbohydrate antigens (CA-19.9 and CA-125) levels were assayed in patients suffering rectal, ovarian, breast and hepatic carcinoma, severe recurrent hepatitis A, chronic persistent hepatitis B, hepatic cirrhosis and in cases of normal pregnancy. Patients with early-stage cancer usually failed to reveal the said antigens.