Asian Pac J Trop Med
June 2011
Objective: To evaluate antiplasmodial and analgesic activities of ethanolic leaf extract/fractions of Panicum maximum.
Methods: The crude leaf extract (47-190 mg/kg) and fractions (chloroform, ethyl acqeous and methanol; 96 mg/kg) of Panicum maximum were investigated for antiplasmodial activity against chloroquine sensitive Plasmodium berghei infections in mice and for analgesic activity against chemical and heat-induced pains. The antiplasmodial activity during early and established infections as well as prophylactic were investigated.