Publications by authors named "Ujjwal Prakash Khanal"
Plain radiographs can still be of considerable diagnostic value for recognizing Brodie's abscess, especially in resource constrained settings.
View Article and Find Full Text PDFArticle Synopsis
- - Aortic aneurysm is a serious condition more common in patients with systemic lupus erythematosus (SLE), often diagnosed through imaging due to vague symptoms.
- - Management involves medication for inflammation and high blood pressure, as well as surgery for larger or symptomatic aneurysms, with ongoing monitoring for complications.
- - The case of a 49-year-old woman highlights the risk of aneurysm rupture, emphasizing the need for vigilant monitoring and timely medical intervention to prevent fatal outcomes.
We report the case of a 62-year-old man who presented with shortness of breath, cough, bilateral lower limbs' swelling, and blackish discoloration of multiple fingertips over the past 2 months. Anti-Ribonucleoprotein antibodies were found to be present, and gadolinium-based cardiac MRI showed non-vascular subendocardial enhancement with diffuse symmetrical thickening of the left ventricular wall. A diagnosis of Mixed connective tissue disease with secondary cardiac amyloidosis was thus made, and the patient was successfully managed with intravenous cyclophosphamide, corticosteroids, and other supportive measures.
View Article and Find Full Text PDFBackground: Toxic epidermal necrolysis (TEN) is a rare, acute and potentially fatal skin condition usually induced by drugs. Although much attention is focused on the life threatening acute cutaneous and sight threatening ocular manifestations of this disease, chronic pulmonary complications like bronchiolitis obliterans are occasionally encountered. However, little is known about its incidence, pathogenesis, clinical course and outcome in children recovering from TEN.
View Article and Find Full Text PDFAim: We aim to review the literature to collate and describe features of encephalitides arising from autoantibodies against leucine-rich glioma-inactivated 1 (LGI1), gamma aminobutyric acid receptor (GABABR), and contactin-associated protein-like 2 (CASPR2) in Asian populations and compare them with findings of Western studies.
Methods: Peer-reviewed articles published till 24 May 2020 were searched, and original, full-text studies from Asia with serum/CSF antibody-based diagnosis and at least 2 patients were selected. Twenty-four studies with 263 patients (139 anti-LGI1, 114 anti-GAGABR, and 10 anti-CASPR2) were included.