Cucurbitane-Type Triterpenoids from the Blood Glucose-Lowering Extracts of and Fruits.

Context: Few vegetables that are commonly consumed in India as part of diet have been claimed for their antidiabetic potential.

Objective: The present study was aimed at evaluating preventive effects of cucurbit vegetables namely, and belonging to family in diabetic hyperglycemia.

Materials And Methods: The fruits of and were extracted with chloroform and fractionated with hexane to prepare an extract rich in moderately polar components.

Cucurbitacins - An insight into medicinal leads from nature.

Cucurbitacins which are structurally diverse triterpenes found in the members of Cucurbitaceae and several other plant families possess immense pharmacological potential. This diverse group of compounds may prove to be important lead molecules for future research. Research focused on these unattended medicinal leads from the nature can prove to be of immense significance in generating scientifically validated data with regard to their efficacy and possible role in various diseases.

Perceptive solutions to anti-filarial chemotherapy of lymphatic filariasis from the plethora of nanomedical sciences.

Introduction: Growing interest in the application of nanotechnology to treat lymphatic filariasis (LF) implies that the imminent medical arsenal of this interesting technology is attractive for health authorities. Currently, they are completely dependent on friendly oral mass drug (anti-filarials) administration to eliminate this morbid disease and are now looking for new alternatives to bring about further improvements.

Areas Covered: A plethora of issues affecting the oral bioavailability of the mainstay human lymphatic filarial drugs, leading to meager pharmacokinetics and pharmacodynamics issues in anti-filarial chemotherapy are identified.

Formulation and evaluation of floating tablets of liquorice extract.

Background: Floating tablets prolong the gastric residence time of drugs, improve bioavailability, and facilitate local drug delivery to the stomach. With this objective, floating tablets containing aqueous extract of liquorice as drug was prepared for the treatment of Helicobacter pylori and gastric ulcers.

Methods: The aqueous extract of liquorice was standardized by HPTLC.