Publications by authors named "Ujjayni Saha"

Article Synopsis
  • * A recent genomic study identified extensively drug-resistant strains of these bacteria from a blood sample of a patient with a specific kidney condition (pauci-immune crescentic glomerulonephritis), utilizing whole-genome sequencing to analyze their characteristics.
  • * The analysis revealed distinct genome sizes and features, including multiple virulence factors and antimicrobial resistance mechanisms, emphasizing the need to understand these polymicrobial infections for better treatment strategies.
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Article Synopsis
  • - Klebsiella pneumoniae is a serious Gram-negative bacterium known for causing infections and developing antibiotic resistance, especially in its hypervirulent forms that are increasingly affecting community health.
  • - A study analyzed 225 K. pneumoniae isolates over a year at a hospital in Pune, India, finding that 76% formed strong biofilms and many carried genes related to antibiotic resistance and virulence.
  • - The research highlights the urgent need for monitoring and managing these infections due to their potential threats to public health, as strong biofilm formation and multidrug resistance were prevalent in the isolates.
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Introduction: The human microbiome is a unique repository of diverse bacteria. Over 1000 microbial species reside in the human gut, which predominantly influences the host's internal environment and plays a significant role in host health. Lactic acid bacteria have long been employed for multiple purposes, ranging from food to medicines.

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