Lavandula angustifolia Mill. inhibits high glucose and nicotine-induced Ca influx in microglia and neuron-like cells via two distinct mechanisms.

Smoking remains a significant health problem in patients with type 2 diabetes mellitus. This study compared intracellular Ca ([Ca]) in microglia, neurons, and astrocytes in the presence of high glucose (HG) and nicotine and evaluated the effects of Lavandula angustifolia Mill. essential oil (LEO) on this process.

Ginsenoside Rb Reduces Hyper-Vasoconstriction Induced by High Glucose and Endothelial Dysfunction in Rat Aorta.

Acute hyperglycemia induces oxidative damage and inflammation, leading to vascular dysfunction. Ginsenoside Rb (Rb) is a major component of red ginseng with anti-diabetic, anti-oxidant and anti-inflammatory properties. Here, we investigated the beneficial effects and the underlying mechanisms of Rb on hypercontraction induced by high glucose (HG) and endothelial dysfunction (ED).

Extract Restores Smooth Muscle Vasorelaxation in Rat Carotid Arteries Even under High Extracellular K Concentrations.

Recent studies showed that (CL) has antihypertensive effects. However, to date, no study has examined the effects of CL on vascular tone under a high extracellular K concentration ([K]). Thus, the present study examined the effect of an extract of (ECL) on the vascular tension of rat carotid arteries exposed to high [K].

Inertia-Acoustophoresis Hybrid Microfluidic Device for Rapid and Efficient Cell Separation.

In this paper, we proposed an integrated microfluidic device that could demonstrate the non-contact, label-free separation of particles and cells through the combination of inertial microfluidics and acoustophoresis. The proposed device integrated two microfluidic chips which were a PDMS channel chip on top of the silicon-based acoustofluidic chip. The PDMS chip worked by prefocusing the particles/cells through inducing the inertial force of the channel structure.

Particle Focusing in a Straight Microchannel with Non-Rectangular Cross-Section.

Recently, studies on particle behavior under Newtonian and non-Newtonian fluids in microchannel have attracted considerable attention because particles and cells of interest can be manipulated and separated from biological samples without any external force. In this paper, two kinds of microchannels with non-rectangular cross-section were fabricated using basic MEMS processes (photolithography, reactive ion etching and anisotropy wet etching), plasma bonding and self-alignment between two PDMS structures. They were used to achieve the experiments for inertial and elasto-inertial particle focusing under Newtonian and non-Newtonian fluids.