[The ocular form of larval toxocariasis in the Czech Republic].

The damage of the eye is one of the clinical syndromes of the Toxocara infection, caused by the migration activity of the Toxocara canis and Toxocara cati larvae. Ocular larva migrans (OLM) lesions mostly occur unilaterally and frequently are diagnosed as retinoblastoma. The typical symptoms of OLM are presented in our publication.

[Diagnosis of the early phase of larval toxocariasis using IgG avidity].

The term avidity used to express the strength of the bond between a serum specimen and a multivalent antigen. It is known that the avidity increases with time after antibody challenge and measurement of the avidity has been used diagnostically. Recently an assay measuring the IgG avidity of various virus infections and of toxoplasmosis was used to distinguish between acute and chronic infection.

Seroprevalence of Toxocara canis infection in Czech Republic.

An enzyme-linked immunosorbent assay (ELISA) with Toxocara canis excretion--secretion (TES) antigen was used for determination the seroprevalence of Toxocara canis infection in healthy population of several districts in Czech Republic. It was found that the seropositivity ranged from 5.8% to 36.

[Alveolar hydatidosis (alveococcosis) in the Czech Republic and its immunodiagnosis].

The frequent contemporary infections with the tapeworm Echinococcus multilocularis in foxes in some districts of the Czech Republic make it necessary to consider the probability of infection of man by the larval stage of this tapeworm in this country. So far there was in the Czech Republic a single case of alveolar hydatidosis (in 1977) in man with a lethal outcome. Foxes Vulpes vulpes increased in the Czech Republic considerably in numbers in recent years, and their infestations with E.

Immunological studies on human larval toxocarosis.

The aim of the study was to characterize the antiparasite humoral response in patients with the syndrome of visceral larval toxocarosis. Specific IgG, specific IgE and total IgE immunoglobulins against Toxocara canis excretory/secretory antigens (TES) were detected by using ELISA technique. Antibody response was studied in complete sera as well as in immunoglobulin fractions (IgG and IgE), isolation of which was performed on Protein A Sepharose.

[Cysticercosis in the Czech Republic].

The authors report 10 cases of cysticercosis registered by the National Reference Laboratory for tissue helminthiasis. Six Czech citizens and four foreigners contracted the disease. Four of 6 Czech citizens were contaminated abroad.

[Isolation of Dirofilaria repens in vitreoretinal findings].

The authors present the case of a 18-year-old patient who reported deteriorated vision and mobile dark shadows on the left eye. Examination revealed in the vitreous body an extremely mobile filiform, worm-like formation, white in colour, of the size of an arteriole, about 9 mm long. In the course of hospitalization the formation was isolated by surgery of the pars plana vitrectomy and subjected to detailed helminthological examination.

[Simultaneous toxoplasmosis and larval toxocariasis infection in the Czechoslovak population].

The authors discuss the coexistence of infection with toxoplasmosis and larval toxocariasis in man. Both these zoonoses are the most widespread and most serious of all tissue parasitoses on the territory of the CSSR. Knowledge of the incidence and frequency of concurrent infections is important for the differential diagnosis and therapy.

[Larval toxocariasis in a 40-year-old man with detection of larvae in a liver biopsy].

A 40-year old cattle feeder has been suffering from indigestion, leukocytosis and conspicuous eosinophilia for about 4 years. A sample of liver tissue was taken during gastrectomy and multiple allergic granulomas rich in eosinophilia leukocytes were found. Toxocara canis was identified in serial sections outside the granulomas.

Contribution to the knowledge of the reliability of some serological tests in detecting spontaneous bovine cysticercosis.

A total of 110 bulls coming from a farm where cysticercosis repeatedly occurred were examined by means of indirect haemagglutination (IHA), microprecipitation in agar (MPA), and indirect immunofluorescence reaction (IFR). Cysticercosis (isolated cysts with live or dead cysticerci) was detected in 29 of them at post-mortem examination. Among the 29 infected animals, positive reactions were obtained in 37.

[Organ reaction and antibody response in experimental bovine cysticercosis].

Antibody response in the course of experimental invasion of calves with the eggs of tapeworm (Taenia saginata) was studied with the use of indirect haemagglutination reaction and microprecipitation in relation to tissue reaction. Indirect haemagglutination was positive for the first time the 21st day, microprecipitation between the 16th and 21st day, at the time of acute pathological changes induced by the developing larvae. In the period of the morphological rest of cysts, beginning about the 50th day p.

Larva migrans lentis.

A unique case of a larva migrans lentis in a 33-year-old female is presented. The intraocular larval (obviously Toxocara) affection was characterized in the first phase by the development of a peripheral chorioretinal granuloma and in the second phase by the finding of larva migrans in the lens. The lively larva appeared several times in the pupillary area under the anterior and posterior lens capsule and survived an intensive treatment by Mintezol.