Publications by authors named "Ugwu J"

Background: Neonatal circumcision is the oldest and most common surgical procedure The safety, ease, and outcomes of various methods of surgical procedures for neonatal circumcision have become increasingly the focus in the reviews of this procedure. This study aimed to identify the easy, safe and acceptable method for neonatal circumcision.

Methods: This prospective study involved 357 male neonates, divided into three groups based on the methods used for neonatal circumcision: artery-forceps, bone-cutter, and Gomco methods.

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Pregnancy leads to a number of structural and functional changes in the urinary system, which makes females susceptible to urological complications. This review aims to discuss the epidemiology, complications and prevention and management of urinary tract infections (UTIs), kidney stones and bladder dysfunction in pregnancy. UTIs are the most common urological problem presenting in 10% of pregnant women; Escherichia coli is the most common causative organism.

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This review explores the integration of sustainable development goals (SDGs) into healthcare organizations in conflict zones, with a specific focus on emergent models aimed at improving population health. The primary objective is to examine how innovative approaches such as telemedicine, mobile health clinics, and community health worker initiatives can be aligned with SDG targets, thereby enhancing healthcare outcomes in conflict-affected regions. The review focuses on the important areas of concern which encompasses technology, infrastructure, community engagement, and social/psychological factors.

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Effective management of health crises requires public health preparedness and response, especially in urban settings where the complexity and scope of catastrophes provide considerable challenges. The integration of project management frameworks with public health policies is highlighted in this review, which investigates the optimization of emergency response systems using a project management methodology. The adoption of cutting-edge technologies that improve real-time monitoring, predictive analytics, and resource allocation such as artificial intelligence (AI), big data, and the Internet of Things (Io-T) is one of the main topics covered.

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Article Synopsis
  • - This study investigates garlic's phytochemical properties and successfully isolates a bioactive compound called 4-chloro-1-(4-methoxyphenyl) hydrazide (BA4C) using gas chromatography-mass spectroscopy (GC-MS).
  • - Preliminary screenings identified various phytochemicals like alkaloids and flavonoids, while computational analyses highlighted the compound's strong intramolecular interactions and reducing properties, especially at its methoxy and hydrazide groups.
  • - BA4C displays favorable binding with key enzymes related to antioxidant activity, such as NADPH dehydrogenase and glutathione reductase, suggesting its potential effectiveness in biological reduction processes.
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Splenic abscess is a life-threatening condition, which is very rare in children. There is usually an infective focus or pre-disposing factors such as immunodeficiencies towards developing splenic abscesses. Only one case of splenic abscess with brain abscesses in an adult has been reported in the English literature.

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Epidemic outbreaks of infectious diseases in conflict zones are complex threats to public health and humanitarian activities that require creativity approaches of reducing their damage. This narrative review focuses on the technology intersection with infectious disease response in conflict zones, and complexity of healthcare infrastructure, population displacement, and security risks. This narrative review explores how conflict-related destruction is harmful towards healthcare systems and the impediments to disease surveillance and response activities.

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Background: Using anthropometric parameters to determine the appropriate Plastibell size before circumcision ensures that cumbersome carrying of all the sizes before each procedure is eliminated and also complications reduced.

Methods: Male neonates who presented for routine circumcision by Plastibell method were recruited. Collected on a proforma were their age in days, weight in Kg, stretched penile length (SPL) in cm, penile diameter (PD) in cm and the Plastibell size used by the "circumciser".

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Eosinophilic myocarditis (EM) is a rare but potentially fatal complication of sustained eosinophilia that is characterized by eosinophilic infiltration into myocardial tissue. There are various etiologies of EM that can be classified into general categories: reactive, clonal, and idiopathic. We present a case of EM caused by chronic eosinophilic leukemia, a rare myeloproliferative neoplasm that frequently presents with sustained peripheral eosinophilia.

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Importance: The clinical characteristics and prognosis of patients with ST-segment elevation myocardial infarction (STEMI) with nonobstructive coronaries (MINOCA) are largely unknown.

Objective: To assess differences in 5-year mortality in patients presenting with STEMI due to MINOCA and MINOCA mimickers as compared with obstructive disease.

Design, Setting, And Participants: A retrospective analysis of a prospective registry-based cohort study of consecutive STEMI activations at 3 regional Midwest STEMI programs.

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Background: Among patients with suspected severe aortic stenosis (AS), Doppler echocardiographic (DE) data are often discordant, and further analysis is required for accurate diagnosis and optimal management. In this study, an automated matrix-based approach was applied to an echocardiographic database of patients with AS that identified 5 discrete echocardiographic data patterns, 1 concordant and 4 discordant, each reflecting a particular pathophysiology/measurement error that guides further workup and management.

Methods: A primary/discovery cohort of consecutive echocardiographic studies with at least 1 DE parameter of severe AS and analogous data from an independent secondary/validation cohort were retrospectively analyzed.

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Classical bladder exstrophy is a congenital anomaly whose management and outcome has advanced over years. Management and outcome are better when management starts at the newborn period. This was the management of a neglected bladder exstrophy in a male presenting at 16 years of age.

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The critical design parameter when sizing a separator is the size of oil droplets in the water phase. This study improves the design of a separator by investigating the parameters that control droplet size, frequency, and distribution. Experimental work was performed to investigate the effect of flow rates and oil layer thickness on these parameters.

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The use of hydrogen is gaining reputation because of its many beneficial properties to the environment in comparison to hydrocarbon not minding its net energy requirement for production challenges. With most countries adopting a strategy to achieve their net-zero emissions targets, it becomes much more important to find affordable, low-carbon ways of producing hydrogen. An innovative method of producing hydrogen from hydrocarbon reservoirs while keeping the associated by-products in the reservoir has been demonstrated researchers from the University of Calgary.

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Background: Circumcision is regarded as the most common surgical procedure world over. It is also perceived to be a simple and safe procedure; however, it could be fraught with major urological complications such as urethrocutaneous fistula (UCF). Repair of these fistulae poses a great reconstructive challenge to the paediatric surgeon/urologist with varied outcomes.

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Background: The prognosis of ST-segment elevation myocardial infarction with non-obstructive coronaries (STE-MINOCA) is largely unknown.

Methods: The objective of this study is to evaluate the prevalence, characteristics, and 5-year mortality of patients with STE-MINOCA compared to STEMI with coronary artery obstruction (STEMI-Obstruction) using a multicenter cohort of consecutive STEMI patients at 3 regional Midwest STEMI programs from 2003 to 2020. STE-MINOCA was defined based on (1) coronary stenosis < 60% by visual estimation, (2) ischemia with elevated troponin, and (3) no alternative diagnosis.

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Objective: This study aimed to compare the effectiveness of interactive media-based dance and art therapies in reducing symptoms of posttraumatic stress disorder among school children in Nigeria who have experienced abduction.

Method: The study utilised a quasi-experimental design using a sample of 470 school children in Nigeria aged 10-18. The participants were divided into three groups, namely control, dance and art therapy groups.

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Introduction: Job stress is highly prevalent in the workforce worldwide, and tends to threaten employees' physical and mental wellbeing, reducing organizational outcomes. The negative impacts of workplace stress on academics have been found to disproportionately interfere with both institutional research productivity and students' learning outcomes. This study analyzed data from a randomized control trial, to validate the effectiveness of cognitive behavioral therapy combined with yoga in treating job-related stress among lecturers from two Universities in South-East, Nigeria.

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Objective: This study set out to investigate the risk of household food insecurity in Nigeria during the novel COVID-19 pandemic using a harmonised dataset of Nigeria's prepandemic face-to-face survey and two waves of the COVID-19 National Longitudinal Phone Survey (NLPS).

Setting: Nigeria.

Participants: A representative sample of 1674 households is used in the analysis.

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Introduction: Transcatheter aortic valve replacement (TAVR) has become a suitable alternative to surgical aortic valve replacement (SAVR) for the treatment of symptomatic severe aortic stenosis (AS). A high proportion of patients with AS have mixed aortic valve disease (MAVD) with mild or more concurrent aortic regurgitation (AR). Differential outcomes of TAVR among patients with AS and MAVD have not been well characterized.

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Pericardial cysts are rare mediastinal masses of congenital etiology. Giant pericardial cysts measuring greater than 10 cm are even rarer. In a small proportion of cases, the natural history of pericardial cyst is one of continuous slow growth.

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Renal artery calcifications can be associated with insufficient stent expansion and in-stent restenosis. Intravascular lithotripsy (IVL) uses shockwaves to disrupt calcium and treat calcific renal in-stent restenosis. Herein, the authors present a case to treat resistant reno-vascular hypertension and in-stent restenosis of an inadequately expanded renal stent in a patient with severe calcific renal artery stenosis.

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Background/objectives: The negative impacts of Job-related burnout on job performance have been widely documented in the literature. Burnout accounts for both physical and mental health outcomes that increase work turnover in teachers, especially those who teach special needs children, like those with Autism Spectrum Disorders (ASD). The current study assessed the effectiveness of Rational Emotive Occupational Health Coaching (REOHC) in minimizing job burnout amongst autistic children teachers in Anambra state, Nigeria.

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Introduction: There is a paucity of data regarding the outcomes of transcatheter aortic valve replacement (TAVR) among patients with thoracic or abdominal aortic aneurysms (AA). Using the Nationwide Inpatient Sample (NIS) database, we explored the safety of TAVR among patients with a diagnosis of AA.

Methods: We queried the National Inpatient Sample database (2012-2017) for hospitalized patients undergoing TAVR, using ICD-9 and ICD-10 codes for endovascular TAVR.

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Sub-Saharan Africa's regulatory environment ranks amongst the least business friendly in the world. The difficulty of starting and operating businesses and the high tax burden are amongst the major conditions that make the regulatory environment hostile. This study examines how these business regulatory conditions explain the growing challenges in mitigating CO emissions in the sub-region.

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