Cytotoxic, antioxidant, and enzyme inhibitory activities of Centaurea stapfiana extracts and their HPLC-ESI-QTOF-MS profiles: Insights into an unexplored Centaurea species.

The members of the genus Centaurea have a great interest in pharmaceutical and nutraceutical fields due to their biological potential. Based on this information, we aimed to evaluate the biological properties (antioxidant, enzyme inhibition and cytotoxicity) and chemical profile of the extract of Centaurea stapfiana, an unstudied species. The highest total phenolic content was found in the ethanol/water extract with 32.

Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens (Boiss. & Noë) Grierson using network pharmacology.

Tanacetum nitens (Boiss. & Noë) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, antioxidant, enzyme inhibition, and cytotoxic properties of T.

Comprehensive metabolite and biological profile of "Sulmona Red Garlic" ecotype's aerial bulbils.

"Sulmona Red Garlic" is a well-known Italian traditional product. Bulbs, used for culinary purposes, have been largely investigated for their medicinal properties whereas aerial bulbils are usually removed as waste material. Here, for the first time, chemical composition and biological properties of the hydroalcoholic extract from aerial bulbils were investigated.

Exploring Sorbus torminalis Leaves: Unveiling a Promising Natural Resource for Diverse Chemical and Biological Applications.

Sorbus torminalis (L.) Crantz has a rich history of versatile applications spanning the fields of medicine and nutrition. It is noteworthy that the decoction obtained from S.

Uncovering chemical profiles, biological potentials, and protection effect against ECM destruction in H O -treated HDF cells of the extracts of Stachys tundjeliensis.

The genus Stachys L., one of the largest genera of the Lamiaceae family, is highly represented in Turkey. This study was conducted to determine the bio-pharmaceutical potential and phenolic contents of six different extracts from aerial parts of Stachys tundjeliensis.

Insight into novel inhibitors from against Cholera via pharmacoinformatics and molecular dynamics simulation approaches.

The underdeveloped countries with large populations are facing a grave global threat in the form of cholera. , the etiologic agent of Cholera has drawn attention recently due to antimicrobial resistance and resulting outbreaks that necessitates establishment of novel medications to counteract virulence and viability of the pathogen. Roxb.

Unraveling the chemical profile, antioxidant, enzyme inhibitory, cytotoxic potential of different extracts from Astragalus caraganae.

Six extracts (water, ethanol, ethanol-water, ethyl acetate, dichloromethane, and n-hexane) of Astragalus caraganae were studied for their biological activities and bioactive contents. Based on high-performance liquid chromatography-mass spectrometry (HPLC-MS), the ethanol-water extract yielded the highest total bioactive content (4242.90 µg g ), followed by the ethanol and water extracts (3721.

Orbitrap Mass Spectrometry-Based Profiling of Secondary Metabolites in Two Unexplored Species and Bioactivity Potential.

The study aimed at the metabolite profiling and evaluation of antioxidant and enzyme inhibitory properties of methanol extracts from flowers, leaves, and tubers of unexplored (Banks & Sol.) Kuntze and (Blume) Schott (Araceae). A total of 83 metabolites, including 19 phenolic acids, 46 flavonoids, 11 amino, and 7 fatty acids were identified by UHPLC-HRMS in the studied extracts for the first time.

Chemical Characterization of Different Extracts from Artemisia annua and Their Antioxidant, Enzyme Inhibitory and Anti-Inflammatory Properties.

Artemisia annua L. (Asteraceae Family) is an important plant in Asia that has been used for treating different diseases, including fever due to malaria, wounds, tubercolisis, scabues, pain, convulsions, diabetes, and inflammation. In this study we aimed to evaluate the effects of different polarity extracts (hexane, dichloromethane, ethyl acetate, ethanol, ethanol/water (70 %) and water) from A.

Yield and Composition of the Essential Oil of the Genus in Turkey.

The genus W. Koch (Apiaceae) is represented by four species in Turkey. The composition of the essential oil of genus members (Apiaceae) growing in Turkey was investigated in this study.

Adding New Scientific Evidences on the Pharmaceutical Properties of Agnew Extracts by Using In Vitro and In Silico Approaches.

is a medicinal plant traditionally used for treating intestinal worms. In the present study, the chemical composition and bio-pharmacological properties of extracts were investigated. Enzyme inhibition and scavenging/reducing properties of water, methanol, and ethyl acetate extracts were assayed.

Which Extraction Solvents and Methods Are More Effective in Terms of Chemical Composition and Biological Activity of from Turkey?

The bioactive content, antioxidant properties, and enzyme inhibition properties of extracts of from Turkey prepared with different solvents (water, methanol, ethyl acetate) and extraction methods (maceration, soxhlet, homogenizer assisted extraction, and ultrasound assisted extraction) were examined in this study. UHPLC-HRMS analysis detected or annotated a total of 50 compounds in extracts, including 18 hydroxybenzoic and hydroxycinnamic acids, 7 Hexaric acids, 7 Coumarins, 15 Flavonoids, and 3 hydroxycinnamic acid amides. The extracts had phenolic and flavonoid levels ranging from 14.

Detailed Chemical Characterization and Biological Propensities of Malabaila lasiocarpa Extracts: An Endemic Plant to Turkey.

This study focused on the biological evaluation and chemical characterization of Malabaila lasiocarpa Boiss. (M. lasiocarpa) (Family: Apiaceae).

Two Medicinal Plants (Alkanna trichophila and Convolvulus galaticus) from Turkey: Chemical Characterization and Biological Perspectives.

The aim of the present study was to quantify selected phenolic compounds, determine antioxidant activity and enzyme inhibitory effects of the aerial parts of Alkanna trichophylla Hub.-Mor. (A.

Chemical Profiling and Biological Evaluation of Extracts and Essential Oil: An Endemic Plant from Turkey.

is a poorly studied, endemic species () of Turkey. For the first time, the biological activities (antioxidant, enzyme inhibition, and cytotoxicity properties) of the hexane, ethyl acetate, methanol, water/methanol, and water extracts and essential oil prepared from aerial parts were assessed. Hydro-methanol (41.

Ethnobotanical study on medicinal plants in villages of Çatak (Van-Turkey).

Ethnopharmacological Relevance: This paper provides significant ethnobotanical information on medicinal plants in the villages of Çatak in the Eastern Anatolia Region. Recording such data calls for urgency. This is the first ethnobotanical study in which statistical calculations about plants are carried out by means of FIC method in Eastern (Van) part of Turkey.

An ethnobotanical study on medicinal plants in Espiye and its surrounding (Giresun-Turkey).

Ethnopharmacological Relevance: This paper provides significant ethnobotanical information on medicinal plants in Espiye in the Black Sea Region. Recording such data calls for urgency. This is the first ethnobotanical study in which statistical calculations about plants are carried out by means of FIC method in Northern (Espiye-Giresun) part of Turkey.

Ethnobotanical study on medicinal plants in Geçitli and its surrounding (Hakkari-Turkey).

Ethnopharmacological Relevance: This paper provides significant ethnobotanical information on medicinal plants in the Geçitli Township in the Eastern Anatolia Region. Recording such data calls for urgency this is the first ethnobotanical study in which statistical calculations about plants are carried out by means of the FIC method in Eastern (Hakkari) part of Turkey. Aim of the study This study aims to identify the wild plants collected for medicinal purposes by locals of Geçitli which is located in the Eastern Anatolia Region of Turkey, and to identify the uses and local names of these wild plants.

Traditional uses of medicinal plants in Solhan (Bingöl-Turkey).

Ethnopharmacological Relevance: This study has identified not only the wild plants collected for medical purposes by local people of Solhan District in the Eastern Anatolia Region, but also the uses and local names of these plants. It tried to provide a source for researchers studying in ethnobotany, pharmacology and chemistry by comparing the information obtained from traditionally used herbs with previous laboratory studies.

Aim Of The Study: This study aims to identify wild plants collected for medical purposes by the local people of Solhan District located in the Eastern Anatolia Region of Turkey and to determine the uses and local names of these plants.

Traditional uses of some medicinal plants in Malatya (Turkey).

Ethnopharmacological Relevance: This study has identified not only the wild plants collected for medical purposes by local people of Malatya Province in the Eastern Anatolia Region, but also the uses and local names of these plants. It tried to provide a source for researchers studying in ethnobotany, pharmacology and chemistry by comparing the information obtained from traditionally used herbs with previous laboratory studies.

Aim Of The Study: In Turkey, use of plants for medical purposes has been a tradition.

Ethnopharmacological survey of medicinal plants in Maden (Elazig-Turkey).

Aim Of The Study: This study aimed to identify wild plants collected for medical purposes by the local people of Maden County, located in the Eastern Anatolia Region of Turkey, and to establish the uses and local names of these plants.

Materials And Methods: Field study was carried out over a period of approximately 2 years (2008-2010). During this period, 131 vascular plant specimens were collected.

An ethnobotanical survey of medicinal plants in Sivrice (Elazığ-Turkey).

Aim Of The Study: This study aimed to identify wild plants collected for medical purposes by the local people of Sivrice County, located in the Eastern Anatolia Region of Turkey, and to establish the uses and local names of these plants.

Materials And Methods: Field study was carried out over a period of approximately two years (2005-2006). During this period, 146 vascular plant specimens were collected.