Cytotoxicity of eluates from a gamma-ray-polymerized poly(methyl methacrylate).

The purpose of this study was to evaluate the cytotoxicity of gamma-ray-polymerized poly(methyl methacrylate) (PMMA). A total of 32 disk-shaped PMMA specimens were polymerized by gamma-irradiation with 1 Mrad for 4 h (Group 1), 2 Mrad for 8 h (Group 2), 3 Mrad for 12 h (Group 3), and thermally polymerized (Group 4). Four- and 6-day eluates of the specimens were prepared in Eagle's Minimal Essential Medium (EMEM) without Fetal Calf Serum (FCS).