[Hyperbaric oxygenation in the complex treatment of patients with aneurysms of the cerebral vessels].

Experience in the use of hyperbaric oxygenation (HBO) in 56 neurosurgical patients with cerebral vascular aneurysms, mainly in the postoperative period, testifies to the expediency of including this method in the complex of therapeutic measures for these patients. The deep oxygenation of the body tissues, the brain included, produced by HBO makes it possible to prevent in many cases the development of severe and stable neurological defects in the postoperative period and contributes to the normalizaion of vitally important functions. Th therapeutic efficacy of the method is more marked when it is applied sufficiently early (before poorly reparable secondary disorders occur in the organism).

[State of central hemodynamics in cerebral arterial aneurysms in the acute period of subarachnoid hemorrhage].

Central hemodynamics was studied by the method of dye (indigo carmine) dilution in 44 persons, 34 of whom had saccular aneurysms of the cerebral arteries in the acute period of subarachnoid hemorrhage and 10 formed the control group. Central hemodynamics changed depending on the condition of the patient. In a satisfactory and moderately severe condition, the cardiac output (minute circulation, volume, stroke volume cardiac index) was increased.

[Visceral pathology in severe cranio-cerebral injuries and its pathogenetic mechanisms].

Pathological conditions of the internal organs and their innervation apparatus, including the limbic cortex, reticular formation, vegetative nuclei of the vagus nerves and spinal cord, peripheral ganglia, and intramural plexuses, in severe craniocerebral trauma were studied by the clinico-physiological, clinico-morphological, and neurohistological methods. The innervation apparatuses of the organs were also studied in experiments with a purposeful effect exerted on the hypothalamus. Peculiarities in the manifestation of visceral pathology in diencephalic and mesencephalobulbar forms of brain lesions were established.

[Several pathophysiologic grounds for radical removal of contusion foci from the cerebral hemispheres].

Local circulation and PO2 of the cerebral tissue were studied in 26 patients during the acute period of a severe craniocerebral trauma. It was demonstrated that pronounced changes in the microcirculation developed in the area of the concussion focus in the cerebral hemispheres. Three zones of disorders in the local circulation were distinguished, and it was shown that in case of an unremoved concussion focus the extending of its necrosis zone took place.

[Surgical treatment of para-stem tumors by a transtentorial approach].

The scope of the interventions and their results, as well as some aspects of the approach are analyzed in 24 cases. Tentoriotomy from the posterior cranial fossa proved technically complicated; its results are unsatisfactory. Somewhat better results were obtained with a combined approach including an incision of the tentorium.

[The role of brain stem lesions in cerebral circulatory disorders accompanying severe cranio-cerebral injuries].

Clinical and anatomical comparisons were undertaken in 23 cases of mortality due to severe craniocerebral injuries. The set of clinical examinations included circulation and brain gas exchange studies. Cerebral circulatory hypoxy was revealed in all the patients, but in cases of its compensated form all signs of brain stem injury were lacking, while in cases of its non-compensated form foci of brain stem injury could be revealed at autopsy.

[Cranio-cerebral hypothermia and neuro-vegetative blockade in the systematic treatment of injuries to the skull and brain].

A method of neurovegetative blockade with and without cranio-cerebral cooling has been worked out to deal with patients with traumas of the cranium and brain of varying severity. Indications for application of the neurovegetative blockade and cranio-cerebral cooling, their intensity and duration have been defined. The application of these methods within the framework of a complex purposeful treatment of severe cerebrocranial traumas made it possible to substantially reduce the lethality among the patients and this pustified recommending it for wide clinical use.