A case report on the loss of an Iglesias resectoscope beak during hysteroscopic myomectomy.

This case report describes the dynamics of the detachment of the ceramic beak of an Iglesias resectoscope that was lost in the uterine cavity during 'cold loop' hysteroscopic myomectomy. Our aim is to increase awareness of this issue and caution our colleagues against using Iglesias resectoscopes for hysteroscopies. The ceramic beak of an Iglesias resectoscope can detach itself if hard tissue is encountered during operative hysteroscopy.

Applying graph theory to improve the quality of scientific evidence from textual information: Neural injuries after gynaecologic pelvic surgery for genital prolapse and urinary incontinence.

Aims: To provide the overall rate for all types of neurologic iatrogenic injuries during urogynaecologic surgery from textual data.

Methods: Systematic research focused on complications of gynaecologic surgery and neurologic injuries in abstracts. Keywords concerning complications (cluster A), unspecific; neurologic issues (cluster B); surgery (generic words) (cluster C); specific gynaecologic operations (cluster D); and specific gynaecologic operations for pelvic organ prolapse and urinary incontinence (cluster E) were extracted.

Looking for Responders among Women with Chronic Pelvic Pain Treated with a Comicronized Formulation of Micronized Palmitoylethanolamide and Polydatin.

Background: Palmitoylethanolamide is reported to solve pain and neuroinflammation in different models of chronic and neurodegenerative diseases. Some concerns have been illustrated for cautiously interpreting the available literature on the topic. Specifically, there is a lack of evidence about palmitoylethanolamide and female chronic pelvic pain.

Assessing the ratio between new Covid-19 cases and new tests for Sars-Cov-2 in Italy by fractal investigation.

Aim: processing the heterogeneous data on the Italian Covid-19 epidemic by fractal investigation on the trend curve of the ratio between new Covid19 cases/new Sars-Cov-2 tests.

Methods: New cases of Covid-19 disease and new tests were calculated from raw data freely available on the Italian governing website. The effectiveness of Italian government Decrees aiming to obtain lock-down was assessed by fractal investigation.

Ursodeoxycholic acid in the treatment of pregnancy cholestasis: a data-set available for Meta-analyses.

Background: The recent literature on intrahepatic cholestasis of pregnancy raises questions on the best management of such a disease. Improved evidence might be achieved by meta-analyses.

Aim: Providing data for allowing individual patients meta-analyses and aggregate data meta-analyses.

Conservative methotrexate treatment of a scar pregnancy case: adding evidence to the evidence.

A single case of ultrasonographic-guided local injection of methotrexate for managing scar pregnancy is reported. The outcome was successful and had no side effects. The case was reported to increase the evidence supporting this type of management.

Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis.

Background: Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of pregnancy, yet its largest trial detected minimal benefit for a composite outcome (stillbirth, preterm birth, and neonatal unit admission). We aimed to examine whether ursodeoxycholic acid affects specific adverse perinatal outcomes.

Methods: In this systematic review and individual participant data meta-analysis, we searched PubMed, Web of Science, Embase, MEDLINE, CINAHL, Global Health, MIDIRS, and Cochrane without language restrictions for relevant articles published between database inception, and Jan 1, 2020, using search terms referencing intrahepatic cholestasis of pregnancy, ursodeoxycholic acid, and perinatal outcomes.

Perspectives of Italian pregnant women on pregnancy examinations and pregnancy care: is the caregiver more important than the care?

Aim: Assessing awareness of Italian low-risk pregnant patients on low-risk pregnancy care and what do they feel about their own pregnancy.

Methods: A questionnaire was administered to 382 low-risk pregnant women. This questionnaire assessed general knowledge of low-risk pregnancy, low-risk pregnancy care, and how much patients rated ten topics of low-risk pregnancy care.

Assessing the regional policies of Italian regions in managing the Cesarean delivery phenomenon: a fractal analysis.

Objectives: Assessing the 2017 administrative data on Cesareans delivery in Italy by using fractal statistic.

Methods: 2017 administrative data on Italian Cesarean deliveries are freely available as crude numbers and rates according to each Italian region, according to Italian health institute type and according to first or repeated Cesarean. As already reported, the Italian Cesarean delivery phenomenon is in relationship with hospital, regional, cultural perspectives in caring pregnancy and delivery.

A pregnant woman and the SARS-CoV-2 infection: how are barriers easily crossed?

A case of SARS-CoV-2 in a pregnant woman is described. How the case has crossed the barriers is highlighted, hoping this will be useful in planning appropriate intervention in cases of infected pregnant women.

Likelihood of Accomplishing an In-Patient Hysteroscopic Myomectomy in a One-Step Procedure: A Systematic Review and Meta-Analysis.

Purpose: To assess the feasibility rate of one-step hysteroscopic myomectomy according to the technique adopted.

Methods: In July 2016, PubMed, ClinicalTrials.gov, SCOPUS, Scielo, and AJOL databases were used for searching references.

Estimate of the proportion of uncertain diagnoses of pudendal neuralgia in women with chronic pelvic-perineal pain: A systematic review with a descriptive data synthesis.

Background: There is a gap between pudendal neuralgia (PN) due to pudendal entrapment syndrome and PN without pudendal entrapment syndrome. The latter could have atypical symptoms.

Aim: Defining a rate of atypical PN from a clinical series of female patients with chronic pelvic-perineal pain.

Data on correction of pelvic organ prolapse by laparoscopic lateral suspension with mesh: A clinical series.

This DIB article provides additional data on laparoscopic lateral suspension with mesh for correcting pelvic organ prolapse. Data come from a multicentric sample of Italian women (https://doi.org/10.

Correction of pelvic organ prolapse by laparoscopic lateral suspension with mesh: A clinical series.

Objective: Illustrating the outcomes of laparoscopic lateral suspension by mesh for pelvic organ prolapse repair.

Study Design: A retrospective observational study was conducted collecting medical records of 48 patients treated between May 2016 and April 2018 in two different centers in Italy. Pre- and post-operative clinical evaluations as well as patients' satisfaction scores were considered.

Which is the destiny of ulipristal acetate for uterine fibroids? A commentary on the Italian medicines agency (AIFA) pronouncements.

The 19 of February 2018 the Italian Medicines Agency (AIFA - Agenzia Italiana del Farmaco) temporary stopped the new administration of Ulipristal Acetate (UPA) for treating uterine leiomyomas symptoms, because liver injury and hepatic failure had been reported in relationship with UPA use. After the European Medicines Agency review of risks of UPA, the 3 of August 2018 the AIFA produced another note, disclosing that a cause-effect relationship between the UPA use and liver injury is not proved and that some patients can be discontinuously treated if surgery is not recommended. However, a close monitoring of hepatic function must be done in Ulipristal users.

Correlations between the proportion of type III female genital mutilations in the series and adverse obstetric outcomes: a short meta-analysis.

Authors have reported that evidence on health harms of female genital mutilation is poor.: Meta-analyzing prospective studies on adverse obstetric outcomes according to the severity of female genital mutilation. Prospective studies were already acknowledged in previous meta-analyses and used for calculations.

What women want? Results from a prospective multicenter study on women's preference about pain management during labour.

Objective: The aim of this study was to assess women preference about pain and duration of labour applying a standardized questionnaire.

Study Design: A prospective multicentre large cohort study was carried out in two different University Hospitals. A standardized questionnaire was proposed before active labour and the day after delivery in order to investigate whether women preferred low pain intensity for a longer labour duration or greater pain intensity for a shorter labour duration.

Another Case of De Novo 3q26.33q27.3 Microdeletion and Its Medicolegal Sequel.

A new case of a de novo 3q26.33q27.3 microdeletion is reported.

Cesarean section in the absence of labor and risk of respiratory complications in newborns: a case-control study.

Aim: To establish if labor and gestational age have an additive effect on the likelihood of newborn respiratory complications.

Methods: Case-control study on singleton pregnancies, delivered between 34 and 41 weeks. Cases were collected among newborns discharged with diagnoses of respiratory complications, as codified by ICD 9 1997.

Micronized palmitoylethanolamide/trans-polydatin treatment of endometriosis-related pain: a meta-analysis.

Aim: To demonstrate clinical effectiveness of micronized palmitoylethanolamide-trans-polydatin combination in reducing endometriotic chronic pelvic pain. Other endometriotic-pains were also assessed.

Methods: Systematic reviews of PubMed, SCIELO, Scopus, and AJOL.

Outcome of endometrial cancer after lymphadenectomy: a single center retrospective analysis with long-lasting follow-up.

Background: Role of lymphadenectomy in endometrial cancer is unclear. Our objective is to assess the role of lymphadenectomy in endometrial cancer.

Methods: The study reviewed retrospectively 829 cases of endometrial cancer from a single non-oncological center from 1981 to 2014.

Risk factors for fatality in amniotic fluid embolism: a systematic review and analysis of a data pool.

Purpose: Investigating risk factors for amniotic fluid embolism (AFE)-induced fatality.

Methods: A systematic review of cases of AFE available on PubMed, Scielo, Scopus and AJOL databases that occurred from 1990 to 2015 was carried out. After careful reading of titles, abstracts and full texts, case reports of AFE were reviewed.

Serendipitous Signs, Symptoms, Laboratory Parameters, and Instrumental Patterns of Amniotic Fluid Embolism: Lessons from an Analysis of Case Reports.

Objective: Serendipitous Signs, Symptoms, Laboratory Parameters, and Instrumental Patterns of Amniotic Fluid Embolism: Lessons from an Analysis of Case Reports.

Study Design: Wide analysis of the case reports on AFE published from 1990 to 2014. A scoring system for quantifying the relevance was attributed to each sign, symptom, laboratory parameter, and instrumental abnormal pattern in AFE cases.