Sites of origin of ventricular premature beats in patients with and without cardiovascular disease evaluated by body surface mapping.

The site of origin of ventricular premature beats (VPBs) was estimated by QRS maps and its distribution in two patient groups was studied. VPB origin was determined by comparing the body surface map of VPBs with that during electrical stimuli applied at various sites of the ventricle. Subjects were 100 patients without obvious underlying cardiovascular disease (Group N) and 289 patients with various heart diseases (Group D).

Ramified pelves and their blood supply of the horseshoe kidney in 2 Japanese.

Gross anatomy of the horseshoe kidney in 2 Japanese patients clarified that the long renal pelvis consists of 4 funnel-shaped tubes (Pelvis renalis ramificata) in the hilus opening in the ventral direction, and that the 4th tube can drain half of the isthmus. The renal artery, on the other hand, divided into 2 dorsal and ventral branches around the long pelvis in the hilus, the latter of which gave rise to the branches to the first and second tubes, but the former the branch to the third. Another artery arose from the lower portion of the abdominal aorta to supply the 4th tube in the half of the isthmus.

Midazolam does not affect the field potentials in the caudal part of the spinal trigeminal nucleus.

The effect of midazolam on the field potentials (FPs) in the caudal part of the spinal trigeminal nucleus following strong electrical stimulation of the upper lip was investigated in Wistar albino rats. The rats received i.p.

Non-linear pharmacokinetics of aprindine hydrochloride in oral administration.

The pharmacokinetics of oral aprindine hydrochloride (in the following briefly called aprindine; Aspenon) were studied in 38 patients with ventricular premature contractions following single or multiple administration. Oral administration of aprindine in a single dose of 100-150 mg resulted in a mean maximal plasma concentration of 0.77 microgram/ml and a mean elimination half-life of 26.

Midazolam and somatosensory evoked potentials.

The effect of midazolam, a water-soluble benzodiazepine, on the somatosensory evoked potentials (SEPs) following strong electrical stimulation of the upper lip, was investigated in Wistar albino rats. SEPs were recorded from the surface of the skull in the contralateral temporal area. A computer was used to obtain the averaged SEPs.

Sedative effects and cardiorespiratory influences of intravenous flunitrazepam premedication.

Sedative effects and the influence on cardiorespiratory functions of flunitrazepam, 0.015 mg/kg intravenously, were studied in 13 healthy adult volunteers. Immediately after administration, 12 of the 13 subjects responded when their names were called, while one subject required gentle patting on the shoulder to evoke a response.

Distribution of abnormal Q waves on body surface in relation to left ventricular wall motion abnormalities in myocardial infarction.

This study was undertaken to determine the possible one-to-one relationship between each site of asynergy of the left ventricle and the body surface area to which ensuing abnormal electrical phenomena are reflected. In 140 post-myocardial infarction (MI) patients, distribution of abnormal Q waves on the body surface was correlated with the abnormal segments of LV wall motion identified by left ventriculography (LVG). Unipolar lead electrocardiograms (ECGs) were recorded from 87 lead points over the precordium and the back with Wilson's central terminal as the reference point.