Short Communication: changes in gait after 12 wk of shoeing in previously barefoot horses.

Farriery can impact gait symmetry and lameness outcomes, but there is limited scientific data documenting these effects. We hypothesized that shoeing previously barefoot horses with plain stamp shoes on the hind hooves would increase gait symmetry, alter hock angles and increase range of motion, and improve lameness scores more than shoeing with traditional fullered shoes. At the start of the study, gait symmetry via wireless inertial motion sensors (IMS), kinematic gait analysis (hock angle and range of motion), and American Association for Equine Practitioner's (AAEP) lameness scoring were completed for 14 barefoot horses.

Beyond Coronativism: The Need For Agape.

In this contribution we focus on togetherness, as one of the key notions in the current COVID-19 crisis. Globally, it is seen as vital to stand and act together to combat the virus, and avoid a tragedy of the commons, in which actors are acting out of self-interest and counterproductively to the general interest. In this essay we analyse the current geographical dissonant developments that the required human togetherness across the globe is facing.

Successful mobilization of Ph-negative blood stem cells with intensive chemotherapy + G-CSF in patients with chronic myelogenous leukemia in first chronic phase.

The aim of the study was to investigate the feasibility of mobilizing Philadelphia chromosome negative (Ph-) blood stem cells (BSC) with intensive chemotherapy and lenograstim (G-CSF) in patients with CML in first chronic phase (CP1). During 1994-1999 12 centers included 37 patients <56 years. All patients received 6 months' IFN, stopping at median 36 (1-290) days prior to the mobilization chemotherapy.

Intensive treatment and stem cell transplantation in chronic myelogenous leukemia: long-term follow-up.

In the present study we combined interferon (IFN) and hydroxyurea (HU) treatment, intensive chemotherapy and autologous stem cell transplantation (SCT) in newly diagnosed chronic myelogenous leukemia patients aged below 56 years, not eligible for allogeneic SCT. Patients who had an HLA-identical sibling donor and no contraindication went for an allogeneic SCT (related donor, RD). After diagnosis, patients not allotransplanted received HU and IFN to keep WBC and platelet counts low.

Comparison of busulphan, hydroxyurea and allogeneic bone marrow transplantation (BMT) in chronic myeloid leukaemia: BMT prolongs survival.

Introduction: Whether busulphan-treated patients develop blastic transformation earlier than hydroxyurea treated has been a controversial issue. In a randomised prospective study, we examined the busulphan versus hydroxyurea influence on time to blast crisis and on survival. When we opened our study in 1984, the clinical benefit of allogeneic bone marrow transplantation (BMT) was not well known; to follow up the long-time outcome of this treatment was therefore of great interest.

A phase I/II study of the MDR modulator Valspodar (PSC 833) combined with daunorubicin and cytarabine in patients with relapsed and primary refractory acute myeloid leukemia.

The cyclosporine analog Valspodar (PSC 833, Novartis Pharma) is a strong inhibitor of the mdr1 gene product p-glycoprotein (pgp). A phase I/II study was conducted in order to evaluate if addition of Valspodar to treatment with daunorubicin and cytarabine, given to patients with primary refractory or relapsed acute myeloid leukemia, could increase the complete remission rate.Fifty-three patients were treated in cohorts of three to six patients.

Long-term follow-up of patients >or=60 yr old with acute myeloid leukaemia treated with intensive chemotherapy.

It is still controversial how to treat elderly patients with acute myeloid leukaemia (AML), and results have been poor with most regimens. We report the long-term results of a randomised study performed by the Leukaemia Group of Middle Sweden during 1984-88 comparing two intensive chemotherapeutic drug combinations. Ninety patients >or=60-yr old with untreated AML were randomly allocated to treatment with daunorubicin, cytosine arabinoside (ara-C), and thioguanine (TAD) (43 patients) or a combination in which aclarubicin was substituted for daunorubicin (TAA) (47 patients).

Intensive chemotherapy in patients with chronic myelogenous leukaemia (CML) in accelerated or blastic phase--a report from the Swedish CML Group.

In attempting to restore the chronic phase (CP) of chronic myelogenous leukaemia (CML), the Swedish CML group utilized an intensive chemotherapy protocol for 83 patients (aged 16-79 years) in accelerated (AP, n = 22) or blastic phase (BC, n = 61). Most patients received a combination of mitoxantrone (12 mg/m2/d) and etoposide (100 mg/m2/d) together with cytosine arabinoside (1 g/m2 b.i.

A radiostereometric analysis of movements of the sacroiliac joints during the standing hip flexion test.

Study Design: The standing hip flexion test was evaluated by using a radiostereometric analysis.

Objectives: To evaluate whether the commonly used standing hip flexion test reflects movement in the sacroiliac joints, or whether the increased load of one sacroiliac joint also reduces the mobility of the other sacroiliac joint according to the theory of form and form closure in the sacroiliac joints.

Summary Of Background Data: The standing hip flexion test, used frequently to analyze sacroiliac joint mobility, is advocated as a test for study of normal or impaired motion in the sacroiliac joint.

A radiostereometric analysis of the movements of the sacroiliac joints in the reciprocal straddle position.

Study Design: A Radiostereometric analysis of the reciprocal straddle position.

Objectives: To evaluate the magnitude of rotation in the sacroiliac joints in the reciprocal straddle position.

Summary Of Background Data: The reciprocal straddle position has been objectified in different studies, using different techniques, to show a sacroiliac motion between 5 degrees and 36 degrees.

Can an external frame fixation reduce the movements in the sacroiliac joint? A radiostereometric analysis of 10 patients.

To evaluate whether a Hoffmann-Slätis frame can reduce movements in the sacroiliac joints, 10 patients (7 women) with severe posterior pelvic pain of long duration were externally stabilized. The movements were analyzed with radiostereometric analysis (RSA) in supine and standing positions, preoperatively and postoperatively with the frame applied. In 2 patients, there was no reduction in the movements with the frame, perhaps because it was not properly tightened.

Pain pattern in pregnancy and "catching" of the leg in pregnant women with posterior pelvic pain.

Study Design: A cross-sectional study of symptoms and signs in pregnant women.

Objectives: To describe the clinical appearance of back pain in pregnancy and the relation between pain distribution and symptoms in women with posterior pelvic pain, in order to shed light on etiologic factors.

Summary Of Background Data: Back pain is common in the general population.

Intensive treatment in order to minimize the Ph-positive clone in CML. Danish-Swedish CML Group.

With the rationale that a significant reduction of the malignant clone in CML might prolong time to metamorphosis, intensive treatment was given to patients < or = 55 years. Six months of hydroxyurea and high dose interferon-alpha (IFN-alpha) was followed by one to three courses of intensive chemotherapy. Patients who had a donor were allotransplanted and patients who became Ph-negative in bone marrow were autotransplanted.

Specified diagnosis in 532 cases of back pain.

In the city of Malmö, Sweden, a project was started to improve the rehabilitation of patients with back pain. Among 532 patients with back pain who were on sick leave for an average of 98 days the year preceding the consultation, very few specific diagnoses were made in spite of a thorough clinical and radiological examination. Only five of the patients were cured by surgery.

The impact of intra-uterine factors on neonatal hip instability. An analysis of 1,059,479 children in Norway.

The records of the Medical Birth Registry of Norway from 1970 through 1988 contain information on maternal health, course of delivery and health of 1,059,479 newborns. The overall prevalence at birth of neonatal hip instability (NHI) was 0.9 percent: 0.

Direct ultrasonographic measurement of femoral anteversion in newborns.

A direct method of ultrasonographic measurement of the anteversion angle of the femoral neck is presented. Normal values based on measurements in 30 random newborns with vertex presentation correspond well with figures from previous autopsy series. The femoral anteversion in breech presentation was found to be on average 10 degrees greater than in vertex presentation (p < 0.

Intensive treatment in order to minimize the Ph-positive clone in chronic myelogenic leukemia.

Several studies indicate that interferon (IFN) treatment, intensive chemotherapy and autologous bone marrow transplantation (ABMT) effectively reduce the Ph-positive clone in Chronic Myelogenic Leukemia (CML). In the present study on patients < or = 55 years, we have combined these three treatment modalities. The aim of the study was to eliminate or minimize the Ph-positive clone to see whether a status of minimal residual or Ph-negative disease could be maintained for a longer period of time.

Effect of effusion on hip joint stability in the newborn. A postmortal study.

In a postmortal study we found that 1 mL fluid injected through the triradiate cartilage into the hip joint of a newborn child was enough to cause instability. This instability persisted even after aspiration of the fluid. The findings were confirmed by ultrasonography.