Subcutaneous emphysema of the lower extremity. A case report.

The case presented is a rare example of subcutaneous emphysema isolated to an extremity. This is a benign condition and should not be confused with necrotizing gas-producing infections. In most cases, the condition rapidly resolves without treatment, usually in less than 48 hr.

AIDS and the duty to warn.

Patients who are diagnosed as having AIDS or as having a positive HIV test have created a dilemma for treating physicians. A physician's duty of confidentiality to the patients is in direct conflict with the duty to warn spouses and other contact persons. This article examines the conflict that physicians now face.

Idiopathic familial acroosteolysis: histomorphometric study of bone and literature review of the Hajdu-Cheney syndrome.

We describe a 27-year-old man with familial acroosteolysis involving 9 fingers. Bone biopsy of an affected digit showed osteolysis with no tetracycline deposition, rare osteoclasts, increased vascularity, and numerous mast cells. In contrast, the iliac crest bone showed active bone remodeling and normal double-tetracycline labeling.

External detection of early microvascular dysfunction after no-flow ischemia followed by reperfusion in isolated rabbit hearts.

To define relationships better between the duration of severe ischemia and microvascular functional integrity with an approach potentially applicable to studies in vivo, the effects of 30 and 60 minutes of global, no-flow ischemia on the coronary vasculature of isolated, perfused rabbit hearts were determined. Residue-detection data, analyzed with a two-compartment model, were used to estimate indices of microvascular function, including the mean-transit time (tBSA) of radiolabeled bovine serum albumin (125I-BSA), vascular into extravascular space clearance, and vascular and extravascular space volumes. It was shown that the Central Volume Principle of tracer kinetics does not hold when transport of label between vascular and extravascular spaces takes place convectively by solvent drag, and a more general expression for tBSA was derived and applied.