Association Between Sexual Dysfunction and Dose of Atypical Antipsychotics: Essential to Learn the Basics.

There is paucity of data on sexual dysfunction associated with atypical antipsychotics in Indian population. We estimated the prevalence of sexual dysfunction and assessed dose dependency, if any, in patients on monotherapy of atypical antipsychotics. This cross-sectional study analyzed the data from patients with F20 to F29 (International Classification of Diseases 10 Revision, ICD-10) receiving monotherapy of risperidone (group 1), olanzapine (group 2), or quetiapine (group 3) for at least 4 weeks.

Implementation of revised national tuberculosis control program guidelines: Practitioner's perspective and awareness-a questionnaire based study.

Background: Strengthening public health services, setting up directly observed therapy short course Centres, introduction of Revised National tuberculosis Control Program (RNTCP) are aimed to eradicate tuberculosis by 2025. The aim of this study was to assess physician's awareness, and perspectives about the recent RNTCP guidelines.

Methods: This was a cross-sectional, opinion deriving, study through a tested, validated, standardized questionnaire that covered the role of physician in the diagnosis or treatment of tuberculosis, and tested their awareness about various aspects of RNTCP guidelines.

Pluchea lanceolata protects hippocampal neurons from endothelin-1 induced ischemic injury to ameliorate cognitive deficits.

Ischemic brain injury is one of the leading causes of death and disability, where lack of disease modifying treatment strategies make us rely on symptomatic relief. Treatment principles from traditional systems of medicine may fill this gap and its validation in modern medicine perspective is important to bring them to mainstream. Here, we evaluated the neuroprotective efficacy of Ayurvedic medicinal herb Pluchea lanceolata in treating ischemic hippocampal injury.

Protective Effect of against Aluminum Chloride-induced Neurotoxicity in Swiss Albino Mice.

Background: Aluminum chloride (AlCl) is a known potent environmental neurotoxin causing progressive neurodegenerative changes in the brain. The herb is commonly known as "Rasana" and used as a nerve tonic in neuroinflammatory conditions in Indian system of medicine.

Objective: To evaluate the neuroprotective activity of hydroalcoholic extract of in chronic AlCl-induced neurotoxicity in Swiss albino mice.

Dilemma of Timing of Administration of Non-Steroidal Anti-inflammatory Agents in Relation to Food in the Prevention of Drug Induced Gastritis: Debusting the Myth.

Background & Objective: We aimed to identify the signals that indicate the possible benefits of administering Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) at the initiation of meal, compared to immediately after food.

Methods: This was a randomized, controlled, pilot study in 160 patients who received only NSAIDs for various pain conditions. Patients were randomized to Group I (control group) -NSAID After Food (AF), Group II-NSAID Before Food (BF), Group III-NSAID BF for 2 days and then crossed over to AF for next two days (CO-1) and Group IV-NSAID AF for 2 days and then crossed over to BF for next two days (C0-2 group).

Assessment of Possible Drug Interactions in Patients with Psoriasis and Associated Comorbid Medical Conditions: An Observational Study.

Background: Associated co-morbidities with psoriasis are treated with concomitant medications apart from the antipsoriatic therapy and the resulting Drug-Drug Interactions (DDI) may affect therapeutic outcome.

Objective: To assess the DDI in psoriatic patients with co-morbidities.

Method: In this prospective observational analysis, 150 prescriptions of psoriatic patients, receiving two or more drugs were analysed using drug interaction checker software.

Estimation of gestational age from gall-bladder length.

Establishing a precise duration of gestation is vital in situations such as infanticide and criminal abortions. The present study attempted to estimate the gestational age of the foetus from gall-bladder length. Foetuses of various gestational age groups were dissected, and the length of the gall bladder was measured.