Anastomotic leaks related to bariatric surgeries are uncommon but are related to increased morbidity and mortality. With the recent advances in intraluminal endoscopic interventions, there are some alternative options to close the leak via over-the-scope-clips/suturing or through-the-scope-clips/suturing or covered stent placement. Herein, we aimed to discuss the efficiency and the role of the through-the-scope suturing technique (X-Tack-160-H, Apollo Endosurgery, Austin, Texas, United States) in two different cases who presented with anastomotic leaks following bariatric surgery.
View Article and Find Full Text PDFIntroduction: There has been increasing interest in artificial intelligence in gastroenterology. To reduce miss rates during colonoscopy, there has been significant exploration in computer-aided detection (CADe) devices. In this study, we evaluate the use of CADe in colonoscopy in community-based, nonacademic practices.
View Article and Find Full Text PDFOur case accurately describes a not infrequent finding that is not well understood by endoscopists. Fibroepithelial polyps are benign and should be considered in the differential diagnosis of anorectal polyp.
View Article and Find Full Text PDFBackground: Juxta-papillary duodenal diverticulum (JPDD) has been associated with obstructive jaundice and ascending cholangitis. Potential mechanisms include periampullary colonization of pathogenic bacteria and mechanical obstruction. However, the relation of JPDD with pyogenic liver abscess (PLA) has not been reported.
View Article and Find Full Text PDFDespite being the most common component of numerous metalloenzymes in the human body, zinc complexes are still under-rated as chemotherapeutic agents. Herein, the present study opens up a key route toward enhanced chemotherapy with the help of two Zn complexes (ZnMBC) synthesized alongside Mannich base ligands to upsurge biological potency. Further, well-established mesoporous silica nanoparticles (MSNs) have been chosen as carriers of the titled metallodrugs in order to achieve anticancer drug delivery.
View Article and Find Full Text PDFCase Rep Gastrointest Med
March 2017
Acute esophageal necrosis (AEN) also known as "black esophagus" or necrotizing esophagitis is a rare syndrome characterized by a striking diffuse patchy or circumferential black appearance of the esophageal mucosa that preferentially affects the distal esophagus and terminates at the gastroesophageal junction. Only 88 patients over a span of 40 years have received this diagnosis, and the prevalence of this disease ranges from 0.001 to 0.
View Article and Find Full Text PDFBACKGROUND Intramural hematomas primarily present in the esophagus or duodenum. We report a case of intramural hematoma in the gastric wall (GIH) secondary to percutaneous endoscopic gastrostomy (PEG) tube placement in a setting of platelet dysfunction. CASE REPORT This case study reviews the hospitalization of a 73-year-old male with a history of chronic kidney disease who was admitted for coronary artery bypass graft surgery and mitral valve repair.
View Article and Find Full Text PDFTrigeminal Neuralgia (TN) is considered as one of the most painful neurologic disorders affecting oro-facial region. TN is often diagnosed clinically based on the patients complete history of pain (severity, duration, episodes etc), relief of pain on test dose of Carbamazepine, regional block of long acting anaesthetic. However, Magnetic Resonance Imaging (MRI) plays an important and confirmatory role in showing Neuro Vascular Conflict (NVC) which is the commonest causative factor for TN.
View Article and Find Full Text PDFBackground: Obtaining quality endoscopic biopsy specimens is vital in making successful histological diagnoses. The influence of forceps cup shape and size on quality of biopsy specimens is unclear.
Aim: To identify whether oval cup or two different serrated jaw biopsy forceps could obtain specimens of superior size.
Case Rep Neurol Med
January 2016
Paraspinal and epidural abscesses are rare conditions often diagnosed later in the disease process that can have significant morbidity and mortality. Predisposing risk factors include diabetes, human immunodeficiency virus, intravenous drug abuse, and previous history of spinal surgery or injection. They can threaten the spinal cord by compressive effect, leading to sensory motor deficits and ultimately paralysis and death.
View Article and Find Full Text PDFIntroduction. Eosinophilic polymyositis (EPM) is a rare cause of rhabdomyolysis characterized by eosinophilic infiltrates in the muscle. We describe the case of a young patient with eosinophilic polymyositis causing isolated severe rhabdomyolysis without systemic involvement.
View Article and Find Full Text PDFMalignancy is characterized by anaplasia, invasiveness, and metastasis. Primary oral squamous cell carcinoma is the most prevalent oral malignancy, but secondary malignancy from distant sites have also been reported. Hepatocellular carcinoma (HCC) is a common primary liver malignancy that frequently metastasizes during the course of the disease, but < 1% of cases show oral involvement.
View Article and Find Full Text PDFThe incidence of premalignant lesions and oral cancers is steadily increasing globally. In spite of advancement in early detection, there is increased mortality and morbidity related to oral cancers. The diagnosis of a dysplastic premalignant lesion of the oral mucosa cannot be based solely on clinical findings.
View Article and Find Full Text PDFPaget disease of bone (PDB) is a chronic progressive disease of the bone of uncertain etiology, characterized initially by an increase in bone resorption, followed by a disorganized and excessive formation of bone, leading to pain, fractures, and deformities. It can manifest as a monostotic or polyostotic disease. The prevalence of PDB is common in the Anglo-Saxon population, but relatively rare in India.
View Article and Find Full Text PDFWorld J Gastroenterol
March 2012
Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the proliferation of specialized, bone marrow-derived langerhans cells and mature eosinophils. The clinical spectrum ranges from an acute, fulminant, disseminated disease called Letterer-Siwe disease to solitary or few, indolent and chronic lesions of the bone or other organs called eosinophilic granuloma. Involvement of the gastrointestinal tract is very rare in LCH.
View Article and Find Full Text PDFClin Exp Gastroenterol
July 2011
Clear liquids are often part of colonoscopy preparation instructions, regardless of the active cleansing agent. Poor understanding of this facet may yield poor preparation with delays in management. We studied comprehension of this facet of colon preparation in an Appalachian population.
View Article and Find Full Text PDFJejunogastric intussusception is an uncommon but potentially life-threatening complication of a previous gastrojejunal anastomosis. Although jejunogastric intussusception was first described in 1914, fewer than 200 cases have been reported in the English literature thus far. Awareness of this rare complication would help in early diagnosis and appropriate management.
View Article and Find Full Text PDFPulse oximetry is a widely used technique in biomedical optics, but currently available pulse oximeters rely on empirical calibration approaches, which perform poorly at low saturations. We present an exact solution for pulse oximetry and show how this can be used as the basis for the development of a semiempirical calibration approach that may be useful, especially at low saturations and variable probe geometries. This new approach was experimentally tested against traditional empirical calibration techniques on transmission pulse oximetry for monitoring of fetal sheep using a minimally invasive spiral probe.
View Article and Find Full Text PDFPurpose: Percutaneous nephrostomy (PCN) is an effective method for achieving temporary drainage of the obstructed urinary system and is usually performed under fluoroscopic guidance alone or more commonly under combined sonographic and fluoroscopic guidance. We undertook a retrospective analysis of 273 PCNs performed solely under ultrasound (US) guidance with the aim of evaluating the technique and the safety and efficacy of the procedure.
Material And Methods: A total of 273 PCN procedures in 267 patients were performed under real-time US guidance using the Seldinger technique.