Biomaterials often struggle with surface properties that hinder their effectiveness in delivering nucleic acids, especially affecting cell adhesion and immune responses.
Low pressure cold plasma technology is explored as an eco-friendly method to enhance the surfaces of materials; in this case, it was used to modify silver nanoparticles with chitosan to improve DNA delivery.
The modified nanoparticles showed better biocompatibility and increased cell uptake, pointing to the potential of plasma treatment in advancing gene delivery mechanisms.