The methanolic extract of downregulates the relative expression of 1 gene in the hypothalamus of Wistar rats: A preliminary report.

Objective: 1 gene expression in the rat hypothalamus was investigated following administration of methanolic extract of (MEHS) to provide mechanistic evidence for the reproductive effect of the MEHS as a potential regulator of 1 gene (which directly controls the hypogonadal axis).

Materials And Methods: This experiment was done using fifteen (15) male rats with average weight of 148 g, randomly grouped into three (3) groups (A-C). Group A was the control group and received no treatment.

Kiss1 gene expression, sperm indices and testicular histopathology following the administration of Hibiscus sabdariffa in rats.

Objective: This study investigated the expression of Kiss1 gene on the testis and the blood of Wistar rats, following the administration of methanolic extract of Hibiscus Sabdariffa (MEHS).

Methods: Fifteen (15) rats with an average weight of 204g were randomly divided into three (3) groups (A-C). Group A was given no treatment and served as the normal control group.

shows no ameliorative potential on ovariectomy-induced hormonal and estrous cycle dysregulation in normal cyclic rats: An experimental study.

Background: (PO) is a widely known plant utilized for its medicinal attributes in the treatment of different illnesses.

Objective: To investigate the effect of methanolic extract of PO (MEPO) on ovariectomy-induced reproductive toxicity in normal cyclic rats.

Materials And Methods: Twenty 10-wk-old normal cyclic rats weighing 110-200 g were randomly divided into four groups (n = 5/group).