Background: The resistance of bacteria to antibiotics, particularly those used for first-line therapy, is an increasing cause for concern. Unfortunately, in Nigeria, much of the antibiotic therapy is not laboratory individualized or even laboratory extrapolated, leading to empirical prescription.
Objective: To determine the prevalence of antibiotic resistance among common pathogens in the University of Nigeria Teaching Hospital (Enugu, Nigeria) and to proffer solutions that will help decrease the prevalence.