Linking phytochemistry to traditional uses and pharmacology of an underexplored genus - : a review.

The genus is one of the ethno-medicinally important genera of the Rubiaceae family which has only received a limited scientific attention, despite coming from a pharmacologically and phytochemically important plant family. The genus has found applications in ethnomedical management of diabetes, stomach disorders, inflammations, cardiovascular diseases, epilepsy, wounds, malaria and fever. To unveil knowledge gaps, stimulate research interest and unravel opportunities for drug discovery from the genus , we have carried out an extensive review on its traditional applications, phytochemistry and pharmacology for the first time.