Publications by authors named "Ubong Silas"

Article Synopsis
  • The study aimed to evaluate the economic and health impacts of hospital-acquired venous thromboembolism (VTE) on patients and healthcare systems across ten countries, including Australia and the UK.
  • A mixed-methods approach was used, including surveys with healthcare professionals and a systematic literature review, leading to the identification of five key clinical specialties: orthopedics, oncology, ICU, cardiology, and obstetrics/gynecology.
  • The total estimated cost of hospital-acquired VTE was $41,280 million, affecting patient mortality rates and accounting for 150,081 deaths, highlighting significant implications for healthcare systems.
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The Cochrane systematic review and meta-analysis published in 2022 that compared videolaryngoscopy (VL) with direct laryngoscopy (DL) for facilitating tracheal intubation in adults found that all three types of VL device (Macintosh-style, hyper-angulated and channeled) reduced the risk of failed intubation and increased the likelihood of first-pass success. We report the findings of a subgroup re-analysis of the 2022 Cochrane meta-analysis data focusing on the Macintosh-style VL group. This was undertaken to establish whether sufficient evidence exists to guide airway managers in making purchasing decisions for their local institutions based upon individual device-specific performance.

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Introduction: Surgical site infection (SSI) is a major complication following hemiarthroplasty surgery for displaced neck of femur fractures. Our aim is to systematically analyse relevant peer-reviewed studies for recent clinical information on the quantitative risk of surgical site infection (SSI) after hemiarthroplasty (HA) of hip fracture patients and on the factors which influence the SSI rates.

Methods: A comprehensive search of electronic databases (PubMed, Cochrane) was performed for clinical articles published between 2005 and 2023 and systematically reviewed with a defined list of inclusion and exclusion criteria.

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Purpose: One of the most challenging tasks in laparoscopic gynecological surgeries is suturing. Knotless barbed sutures are intended to enable faster suturing and hemostasis. We carried out a meta-analysis to compare the efficacy and safety of V-Loc barbed sutures (VBS) with conventional sutures (CS) in gynecological surgeries.

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Purpose: Operation rooms have a large environmental impact. Single-use staplers (SUS) are widely used surgical instruments that contribute to resource consumption and waste generation, whereas multi-use staplers (MUS) can greatly reduce the environmental impact of surgery. The staple lines are often reinforced with buttressing material to prevent leaks and bleeding.

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Article Synopsis
  • Targeted therapy for cancer is increasingly reliant on molecular testing, but delays in the testing process can hinder timely treatment initiation.
  • A study analyzed the impact of implementing an in-house next-generation sequencing (NGS) machine for testing metastatic non-small cell lung cancer (mNSCLC) in a hospital, comparing it to the standard practice of sending tests to external labs.
  • Results indicated that in-house NGS could lead to higher testing costs but substantially increased hospital revenue and reduced turnaround time, ultimately improving access to targeted therapy for patients.
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Objective: To evaluate the cost-effectiveness of using mechanical thromboprophylaxis for patients undergoing a cesarean delivery in Brazil.

Methods: A decision-analytic model built in TreeAge software was used to compare the cost and effectiveness of intermittent pneumatic compression to prophylaxis with low-molecular-weight heparin or no prophylaxis from the perspective of the hospital. Related adverse events were venous thromboembolism, minor bleeding, and major bleeding.

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