Comparison of AI applications and anesthesiologist's anesthesia method choices.

Background: In medicine, Artificial intelligence has begun to be utilized in nearly every domain, from medical devices to the interpretation of imaging studies. There is still a need for more experience and more studies related to the comprehensive use of AI in medicine. The aim of the present study is to evaluate the ability of AI to make decisions regarding anesthesia methods and to compare the most popular AI programs from this perspective.

Fractal analysis of jawbone structure in patients with rheumatoid arthritis.

Purpose: Periarticular and generalized osteoporosis are well-known comorbidities of rheumatoid arthritis (RA), associated with either the disease itself or glucocorticoid therapy. This study was performed to quantitatively evaluate changes in the jawbones of patients with RA using fractal analysis (FA).

Materials And Methods: The study comprised 186 participants, including 144 women and 42 men.

Real-Time Tractography-Assisted Neuronavigation for Transcranial Magnetic Stimulation.

State-of-the-art navigated transcranial magnetic stimulation (nTMS) systems can display the TMS coil position relative to the structural magnetic resonance image (MRI) of the subject's brain and calculate the induced electric field. However, the local effect of TMS propagates via the white-matter network to different areas of the brain, and currently there is no commercial or research neuronavigation system that can highlight in real time the brain's structural connections during TMS. This lack of real-time visualization may overlook critical inter-individual differences in brain connectivity and does not provide the opportunity to target brain networks.

Milk ladder: Who? When? How? Where? with the lowest risk of reaction.

The milk ladder (ML) approach, which is the gradual reintroduction of the milk allergen from the least allergenic forms to the most allergenic forms into the diet of the patients, has been utilized mostly in non-IgE-mediated but in some countries also in IgE-mediated-CMPA due to its possible benefits which include nutrition, quality of life and tolerance induction. Despite increasing interest, so far, there is no guideline on ML; thus, the use of this approach shows discrepancies among healthcare professionals as many factors such as dietary habits, patient history, test results, workload, and facilities of the hospitals, the anxiety of the parents/patients may affect the decision on how, when, where and whom to use ML. Here, we reviewed current data on implementing the ML, suggested a 4-step ML including receipts and amounts, and shared our experience on optimal patient selection, appropriate time and steps for initiating ML, and time intervals between the steps targeting the lowest risk of reaction.

A Numerical Study of Topography and Roughness of Sloped Surfaces Using Process Simulation Data for Laser Powder Bed Fusion.

The simulation of additive manufacturing has become a prominent research area in the past decade. Process physics simulations are employed to replicate laser powder bed fusion (L-PBF) manufacturing processes, aiming to predict potential issues through simulated data. This study focuses on calculating surface roughness by utilizing 3D surface topology extracted from simulated data, as surface roughness significantly influences part quality.

Gold nanoparticles decorated FOLFIRINOX loaded liposomes for synergistic therapy of pancreatic cancer.

Pancreatic cancer is predicted to be the second highest cause of cancer deaths by 2030, with a mortality rate of 98 % and a 5-year survival rate of only 4-8 %. FOLFIRINOX which consists of four main ingredients has shown superior efficacy in treating patients with pancreatic cancer compared to other agents and combinations. However, toxicities have prevented full-dose use of FOLFIRINOX.

A Review on the Analysis of Chiral Molecules as Disease Biomarkers by LC/MS.

The chiral compounds may be biomarker candidates in human metabolism, which indicates the health status of humans. There are many applications in LC/MS that show that chiral small molecules are promising biomarkers for human diseases. Both clinical and commercial analyses of chiral metabolites are necessary due to the enantiomeric ratios of chiral molecules in biological samples may show both human health status and diseases.

A mitochondrial redox switch licenses the onset of morphogenesis in animals.

Embryos undergo pre-gastrulation cleavage cycles to generate a critical cell mass before transitioning to morphogenesis. The molecular underpinnings of this transition have traditionally centered on zygotic chromatin remodeling and genome activation, as their repression can prevent downstream processes of differentiation and organogenesis. Despite precedents that oxygen depletion can similarly suspend development in early embryos, hinting at a pivotal role for oxygen metabolism in this transition, whether there is a chemical switch that licenses the onset of morphogenesis remains unknown.

Target gene variations of PPAR isoforms may contribute to MODY heterogeneity: A preliminary comparative study with type 2 diabetes.

Aims: The objective of this study was to evaluate the associations of several genetic variants of peroxisome proliferator-activated receptors (PPARs) on clinical and laboratory parameters in patients with maturity-onset diabetes of the young (MODY), and possible contribution to heterogeneity of the disease.

Methods: The study groups comprised patients with MODY (genetically confirmed (n = 28), clinically relevant but genetically unconfirmed; MODYX (n = 56)), type 2 diabetes mellitus (T2DM; n = 94) and healthy controls (n = 153). PPARA-L162V-(rs1800206), PPARG-C161T-(rs3856806), P12A-(rs1801282), and PPARB/D + 294 T/C-(rs2016520) polymorphisms were genotyped by real-time-PCR.

YouTube as a source of information in cardiopulmonary resuscitation for 2020 AHA Resuscitation Guidelines.

Background: The Internet has transformed global information access, particularly through platforms like YouTube, which launched in 1995 and has since become the second largest search engine worldwide with over two billion monthly users. While YouTube offers extensive educational content, including health topics like cardiopulmonary resuscitation (CPR) and basic life support (BLS), it also poses risks due to potential misinformation. Our study focuses on evaluating the accuracy of CPR and BLS videos on YouTube according to the latest 2020 American Heart Association (AHA) guidelines.

Evaluation of the Effect of Ayres Sensory Integration® Intervention on Balance, Speech and Sensory Processing Skills in a Child with Bilateral Incomplete Partition Type 1: A Case Report.

Purpose: It was aimed to investigate the effects of Ayres Sensory Integration based intervention on balance, speech, and sensory processing skills of a 4-years and 11-month-old child with bilateral incomplete partition type 1 inner ear anomaly and using bilateral cochlear implant.

Method: The child received the Ayres sensory integration-based intervention program for 2 months in 45-minute sessions twice a week. Before and after the intervention, Meaningful Auditory Integration Scale, Categories of Auditory Performance-II for auditory perception evaluation, Test of Early Language Development -Third Edition, Speech intelligibility rating test for evaluating language-speech skills, Evaluation in Ayres Sensory Integration® (EASI), and Dunn Sensory Profile for sensory processing skills were used.

Decoding the influence of emotional and attentional states on self-control using facial analysis.

Self-control plays a pivotal role in pursuing long-term goals related to health and financial well-being. While ample evidence suggests that humans are prone to occasional self-control lapses, little is known about how changes in emotional and attentional states affect the ability to maintain self-control. In two studies (N = 109 and N = 90), we used emotion recognition software to decode participants' facial expressions while manipulating their attentional and emotional states during a Psychomotor Vigilance Task (PVT) before exerting self-control in a subsequent task.

The effect of Mobile-Assisted training and counseling on nurses' ventrogluteal injections application of nursing: A mixed method study.

Background: Nurses often administer intramuscular (IM) injections. However, they do not use the ventrogluteal (VG) site, although it is highly recommended.

Aim: This study investigated whether a mobile-assisted training and counseling program (intervention) encouraged nurses to use the VG site to administer IM injections.

Türkiye's 3-Year Coronavirus Disease 2019 Publication Performance in the Shadow of the Pandemic: A Bibliometric Analysis.

The pandemic created by coronavirus disease 2019 (COVID-19) has led researchers to study to deal with this infection. The number of studies about it being performed and published is increasing over time. Due to the dramatic growth of COVID-19 scientific publications, we conducted a bibliometric and visualized study to better understand the progress, collaborations, and trend topics of COVID-19 publications in Türkiye.

Effect of radiation dose rates and cisplatin on cytogenetic damage in rats receiving head-neck radiotherapy.

Background: We aimed to investigate effect of radiotherapy (RT) applications with different dose rates on cytogenetic damages, which focused on micronucleus (MN) formation, and evaluate how this damage varies by cisplatin in rats receiving head-neck RT.

Material And Methods: Thirty-six Sprague Dawley rats were divided into five groups. The first and second groups were irradiated at a dose rate of 300 monitor unit/minute (MU/min) and 600 MU/min, respectively.

Flexure Performance of Textile-Reinforced Cementitious Composites with Novel Inclined Reinforcements.

Textile-reinforced cementitious composites have great potential to offer novel design opportunities for thin-section structures thanks to their superior material capabilities. In this work, new cementitious composites with novel reinforcement configurations are developed, which have superior mechanical properties. The cementitious composites contain inclined through-the-thickness reinforcements, and their enhanced performance on thin-section material hardening under flexural loading is demonstrated.

Effects of DK With Periodontal Therapy in Diabetes Mellitus and Stage I-II Periodontitis Patients.

Background: The aim of this study is to look into the clinical and biochemical outcomes of DK supplementation in addition to nonsurgical periodontal treatment (NSPT) for patients suffering from diabetes mellitus (DM) and periodontitis.

Methods: Thirty-eight participants with DM and periodontitis were randomized into two different groups. The test group provided NSPT with DK whereas the control group received NSPT with placebo.