Synthesis, Characterization, and Investigation of Corona Formation of Dipeptide-Based Nanomaterials.

Peptide-based nanomaterials can be easily functionalized due to their functional groups, as well as being biocompatible, stable under physiological conditions, and nontoxic. Here, diphenylalanineamide-based nanomaterials (FFANMs) were synthesized, decorated with Ca ions to set the surface charge, and characterized for possible use in gene delivery and drug release studies. FFANMs were characterized by SEM, TEM, dynamic light scattering (DLS), and LC-MS/MS.

Evaluation of the effect of tartrazine on the offspring rats in an in vivo experimental model.

Tartrazine, an azo dye prevalent in pharmaceuticals and food items, was investigated for its impact on fetal development, specifically examining visceral and skeletal abnormalities in rat offspring exposed to daily oral doses throughout pregnancy. Fourteen pregnant rats were randomly assigned to control and tartrazine groups (seven animals each), with tartrazine administered via oral gavage at 7.5 mg/kg throughout gestation.

Improved intracochlear biopolymeric drug delivery system: an study.

Background: The delivery of drugs into the inner ear is a challenging field of study due to the complex cochlear anatomy and physiology. The creation of an intracochlear device that allows for short- and long-term intracochlear delivery of the drugs with a minimal invasive technology is needed to prevent or treat conditions that can potentially prevent the development of permanent hearing loss.

Aim: This study intends to test the efficacy of DXM-infused PLGA microneedles created in our laboratory in an animal model of acute ototoxic injury.

Liver Regeneration Following Thermal Ablation Using Nanocarrier Mediated Targeted Mesenchymal Stem Cell Therapy.

Purpose: To test the efficacy of nanocarrier (NC) mediated mesenchymal stem cell (MSC) therapy for liver regeneration following thermal ablation of porcine livers.

Materials And Methods: Liver radiofrequency ablation was performed in 18 swines divided into MSC, MSC + NC and control groups. The test groups received infusion of MSC or MSC + NC labeled with enhanced green fluorescent protein (eGFP) via hepatic artery.

Corrosion inhibition performance of benzimidazole derivatives for protection of carbon steel in hydrochloric acid solution.

This paper presents a comprehensive study on the corrosion inhibition properties of new organic compounds, (1-benzimidazol-2-yl)methanethiol (LF) and 1-dodecyl-2-((dodecylthio)methyl)-1-benzimidazole (LF), have been examined for inhibiting of Carbon-Steel (C.S) in 1.0 M HCl.

Refractive Error Impact on Video Head Impulse Test Outcomes.

Objective: The objective of this study is to investigate the potential influence of refractive error on Video Head Impulse Test outcomes.

Material And Methods: Eighty-two patients were included in the study, and all patients underwent video head impulse testing. Patients were divided into four groups according to their refractive error: myopia, myopia-astigmatism, astigmatism, and emmetropia as control.

Fatty infiltration and morphology of cervical muscles in patients with temporomandibular disorders: A case-control study.

Background: Changes in the fatty infiltration and/or muscle volume of neck muscles can alter cervical spine alignment and cranial load distribution, which may cause pain in the orofacial region.

Objectives: The aim of the study was to examine the muscle volume and fatty infiltration of neck muscles in patients with temporomandibular disorders (TMD).

Material And Methods: This case-control study included 18 patients with TMD and 18 ageand sex-matched controls.

Early Detection of Ventilator-associated Pneumonia From Exhaled Breath in Intensive Care Unit Patients.

Objective: Evaluate associations between volatile organic compounds (VOCs) in heat and moisture exchange (HME) filters and the presence of ventilator-associated pneumonia (VAP).

Background: Clinical diagnostic criteria for VAP have poor interobserver reliability, and cultures are slow to result. Exhaled breath contains VOCs related to gram-negative bacterial proliferation, the most identified organisms in VAP.

Experimental and theoretical insights into Artemisia Stems aqueous extract as a sustainable and eco-friendly corrosion inhibitor for mild steel in 1 M HCl environment.

The present research demonstrates an innovative investigation of environmentally friendly mild steel (M-steel) corrosion inhibition using the artemisia stems aqueous extract (ASAEx) as an inhibitor in hydrochloric acid 1 M. The standard extraction technique of hydrodistillation was used for producing the aqueous solutions of ASAEx. To assess the ratios of the chemical components, phytochemical screening was used to identify the stems of this plant.

Characterization of fire investigators' polyaromatic hydrocarbon exposures using silicone wristbands.

Background: Exposures to polyaromatic hydrocarbons (PAHs) contribute to cancer in the fire service. Fire investigators are involved in evaluations of post-fire scenes. In the US, it is estimated that there are up to 9000 fire investigators, compared to approximately 1.

The effect of continuous long-term illumination with visible light in different spectral ranges on mammalian cells.

One of the biggest challenges in tissue engineering and regenerative medicine is to ensure oxygen supply of cells in the (temporary) absence of vasculature. With the vision to exploit photosynthetic oxygen production by microalgae, co-cultivated in close vicinity to oxygen-consuming mammalian cells, we are searching for culture conditions that are compatible for both sides. Herein, we investigated the impact of long-term illumination on mammalian cells which is essential to enable photosynthesis by microalgae: four different cell types-primary human fibroblasts, dental pulp stem cells, and osteoblasts as well as the murine beta-cell line INS-1-were continuously exposed to warm white light, red or blue light over seven days.

Risk of hearing loss in the opposite ear after tympanomastoidectomy.

Purpose: The definitive treatment for chronic suppurative otitis media is surgery. Surgical technique and procedure varies according to individual case findings and pathology and may require mastoidectomies in which the canal wall is preserved or lowered to eradicate disease from mastoid air cells. Surgical treatment of chronic middle ear disease carries a risk of damage to the inner ear.

Nodes for modes: nodal honeycomb metamaterial enables a soft robot with multimodal locomotion.

Soft-bodied animals, such as worms and snakes, use many muscles in different ways to traverse unstructured environments and inspire tools for accessing confined spaces. They demonstrate versatility of locomotion which is essential for adaptation to changing terrain conditions. However, replicating such versatility in untethered soft-bodied robots with multimodal locomotion capabilities have been challenging due to complex fabrication processes and limitations of soft body structures to accommodate hardware such as actuators, batteries and circuit boards.

An Unusual Case: Nasolacrimal Stent Penetrating the Oral Cavity.

Lacrimal bypass tubes create a fistula from the conjunctiva to the lacrimal sac or the nasal cavity. Fluoroscopic nonoperative placement of a plastic stent has shown successful results in the treatment of epiphora. Polyurethane lacrimal stents have been reported as a safe, easy, non-surgical treatment in the treatment of distal lacrimal obstruction.

COVID-19 and vaccination in hereditary angioedema: Single center experience.

Like many microbial agents, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its vaccination may increase the frequency and/or severity of attacks. We aimed to observe/evaluate patients with hereditary angioedema (HAE) followed by Sakarya University Research/Training Hospital pediatric allergy unit, Sakarya, Türkiye, for the effects of SARS-CoV-2 infection and COVID-19 vaccination. Ten HAE patients-3 males and 7 females-were evaluated retrospectively.

Novel Indices for Lumbar Discectomy: Systemic Immune Inflammation Index, Systemic Inflammatory Response Index, Multi Inflammatory Index, and Prognostic Nutrition Index.

Aim: To evaluate systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), multi-inflammatory index (MII), and prognostic nutrition index (PNI), and to compare them with the previously reported inflammation-related hematologic index in lumbar discectomy (LD).

Material And Methods: This was a retrospective, cross-sectional, single-center study with 105 consecutive patients who underwent surgery for LD. The study comprised three groups: Group I included data from healthy participants, Group II included data before LD, and Group III included data after LD.

Fracture strength of endocrowns after thermomechanical aging.

This in-vitro study aimed to evaluate the fracture strength (FS; N) of composite, feldspathic, and glass-ceramic computer-aided design/computer-aided manufacturing (CAD/CAM) endocrowns after thermomechanical aging. Seventy non-carious human molars were randomly divided into seven groups, according to the CAD/CAM material used for endocrown fabrication. Intact molars without cavity preparations were used as control (n = 10).

Phenolic Content Analysis of Two Species Belonging to the Family: Antioxidant, Anticholinergic, and Antibacterial Activities.

The family are utilized as ornamental, medicinal, and food supplements throughout the world. The current study focuses on a comparative analysis of the phenolic compositions and bioactivities (including antioxidant, anticholinergic, and antibacterial activities) of ethanolic extracts derived from the aerial parts of the two species ( L. and Boiss).